Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
102 Results for "
spreadability
" in MedChemExpress (MCE) Product Catalog:
Products (102)
102 Results for "spreadability" in MCE Product Catalog:
Cat. No.: HY-P99648
CAS No.: 1788032-39-2
Synonyms: BMS-986168; IPN007; BIIB092
Target:
Domaines de recherche:
Cat. No.: HY-18684
CAS No.: 35899-54-8
Synonyms: 5'-Isobutylthioadenosine; 5'-Deoxy-5'-isobutylthioadenosine
Domaines de recherche:
SIBA (5'-Isobutylthioadenosine) is a transmethylation inhibitor (SAH (HY-19528) analogue), with potent anti-proliferative activity. SIBA reversibly inhibits the production of HSV-1 by blocking methylation, specifically by blocking the 5' end-capping of viral mRNA. SIBA also inhibits the growth of tumour cells in vitro and metastatic spread in vivo. SIBA can be used in cancer, HSV-1 infection and anti-malaria studies .
Cat. No.: HY-164288
CAS No.: 2287331-29-5
Synonyms: TDI-006570
Target:
Domaines de recherche:
TDI-6570 (TDI-006570) is a blood-brain barrier-permeable, orally active cGAS inhibitor with an IC50 of 1.64 μM. TDI-6570 exhibits high gastrointestinal absorption and a long brain half-life in mice, and shows no toxicity to primary neurons. By inhibiting the cGAS-STING-IFN signaling pathway, TDI-6570 reduces STING levels and the activation of TBK1, blocks double-stranded DNA-induced cGAS activation and downstream interferon-stimulated gene expression, thereby reducing tau protein spread and improving synaptic loss. TDI-6570 reverses memory deficits, increases the amplitude of long-term potentiation, enhances the MEF2C transcriptional network, restores PSD-95 and vGAT punctate structures, and significantly improves cognitive resilience. TDI-6570 can be applied to the research of Alzheimer's disease, Parkinson's disease, systemic lupus erythematosus, as well as various central nervous system and autoimmune diseases .
Cat. No.: HY-P0306
CAS No.: 125720-21-0
Synonyms: Heparin Binding Peptide
Target:
Domaines de recherche:
Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells .
Cat. No.: HY-P9932
CAS No.: 1351337-07-9
Synonyms: ETI 204
Target:
Domaines de recherche:
Target:
Domaines de recherche:
Ormetoprim is a veterinary antimicrobial which commonly used in aquaculture and poultry industries. Ormetoprim can be used to prevent the spread of disease in freshwater aquaculture and promote growth in farm animals .
Cat. No.: HY-P4102
CAS No.: 1810853-35-0
Target:
Domaines de recherche:
Cat. No.: HY-P3524
CAS No.: 99896-88-5
Target:
Domaines de recherche:
Cat. No.: HY-D1704
CAS No.: 849464-08-0
RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines .
Cat. No.: HY-N16039
CAS No.: 126221-76-9
Category:
Target:
Cat. No.: HY-158218
Synonyms: Gelatin Methacryloyl, 30% methacrylation, Red Fluorescent
Application: cell culture, biological 3D printing, tissue engineering, etc.
Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Target:
Domaines de recherche:
Target:
Domaines de recherche:
PDDC is a compound used to inhibit Alzheimer's disease. It is a nSMase2 inhibitor that can inhibit tau-induced nSMase2 activity and ceramide elevation, and slow the spread of tau in mouse models.
Cat. No.: HY-P3035
CAS No.: 122929-08-2
Domaines de recherche:
Cat. No.: HY-172476
DSPE-PEG2000-YIGSR is a PEG compound which composed of DSPE and a biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin binding protein (LBP) and promotes adhesion and spreading of a large number of cell types including endothelial cells, fibroblasts and smooth muscle cells. DSPE-PEG2000-YIGSR can be used for drug delivery .
Cat. No.: HY-P0131
CAS No.: 110590-60-8
Synonyms: Laminin (925-933)
Target:
Domaines de recherche:
Cat. No.: HY-158217
Synonyms: Gelatin Methacryloyl, 30% methacrylation, Green Fluorescent
Application: cell culture, biological 3D printing, tissue engineering, etc.
Cat. No.: HY-158217A
Synonyms: Gelatin Methacryloyl, 60% methacrylation, Green Fluorescent
Application: cell culture, biological 3D printing, tissue engineering, etc.
Cat. No.: HY-B0693A
CAS No.: 128345-62-0
Target:
Domaines de recherche:
Ranitidine bismuth citrate is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine bismuth citrate antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine bismuth citrate has selectivity for SARS-CoV-2-infected cells. Ranitidine bismuth citrate also has anti-Helicobacter pylori infection. Ranitidine bismuth citrate inhibits breast tumor development and spread in mice .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
