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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4988 Results for "
expression
" in MedChemExpress (MCE) Product Catalog:
Products (4988)
4988 Results for "expression" in MCE Product Catalog:
Cat. No.: HY-P5642A
Synonyms: RC-101 TFA
Target:
HIV SARS-CoV Influenza Virus Flavivirus HSV Bacterial Fungal Toll-like Receptor (TLR) Ser/Thr Protease
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Cat. No.: HY-P990134
Target:
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Cat. No.: HY-P990291
Target:
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Cat. No.: HY-P990947
CAS No.: 2868265-50-1
Synonyms: AZD9592 Antibody
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Cat. No.: HY-P991202
Target:
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Cat. No.: HY-P99914
CAS No.: 2559704-23-1
Synonyms: GNC-038
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Cat. No.: HY-W009203R
CAS No.: 30925-07-6
Cat. No.: HY-W010037R
CAS No.: 121-00-6
Category:
Target:
Cat. No.: HY-W010066R
CAS No.: 28822-73-3
Category:
Human Gut Microbiota Metabolites Microorganisms Disease markers Endocrine diseases Phenols Polyphenols Nervous System Disorder Endogenous metabolite
Target:
Cat. No.: HY-W010697S
Cholesteryl linoleate-d11 is the d11-labeled Cholesteryl linoleate (HY-W010697). Cholesteryl linoleate is a cholesteryl ester with antibacterial activity that is present in low-density lipoprotein (LDL) particles, human nasal fluid, and respiratory epithelial secretions. Cholesteryl linoleate is oxidized by 12/15-lipoxygenase in macrophages and participates in selective uptake and efflux via LDL receptor-related protein. Cholesteryl linoleate does not induce endothelial adhesion molecule expression, nor does it induce monocyte binding to endothelial cells. Cholesteryl linoleate liposomal formulations inhibit the growth of multiple bacteria at physiological nasal fluid concentrations and act synergistically with antimicrobial peptides. Cholesteryl linoleate is useful for research related to atherosclerosis and bacterial infections .
Cat. No.: HY-W012278S
CAS No.: 1718-53-2
Synonyms: Tetraphene-d12
Research Areas:
Benz[a]anthracene-d12 (Tetraphene-d12) is the deuterated-labeled Benz[a]anthracene (HY-W012278). Benz[a]anthracene (Tetraphene) is a polycyclic aromatic hydrocarbon pollutant and also a ligand of aryl hydrocarbon receptor 2 (AHR2), with a pIC50 of 7.319. Benz[a]anthracene can be detected in spruce needles near aluminum smelters. Exposure to Benz[a]anthracene during zebrafish embryonic stage activates the AHR-CYP1A signaling pathway and induces AHR2 expression, leading to social behavioral deficits that persist into adulthood, accompanied by impaired neuro-immune interaction, while anxiety levels remain unaffected. Benz[a]anthracene can be used in studies related to PAH environmental toxicology, developmental neurotoxicity and biodegradation .
Cat. No.: HY-W012572
CAS No.: 351-50-8
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D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu 2+) .
Cat. No.: HY-W012572A
CAS No.: 328526-86-9
Target:
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Cat. No.: HY-W015600
CAS No.: 614-80-2
Synonyms: Orthocetamol
Research Areas:
2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Cat. No.: HY-W016773S
CAS No.: 347841-78-5
Cat. No.: HY-W017443R
CAS No.: 5794-13-8
Category:
Cat. No.: HY-W017443S1
CAS No.: 204451-47-8
Cat. No.: HY-W021448S
CAS No.: 1173020-63-7
Synonyms: Guanidinoacetic acid-d2
Cat. No.: HY-W021448S1
CAS No.: 2483829-93-0
Synonyms: Guanidinoacetic acid-15N,13C2
Cat. No.: HY-W040045R
CAS No.: 18466-51-8
Synonyms: Pelargonidin-3-O-glucoside chloride (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
