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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
ABCG
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "ABCG" in MCE Product Catalog:
Cat. No.: HY-155653
CAS No.: 2559759-59-8
ABCG2-IN-2 is a potent ABCG2 inhibitor with favorable oral pharmacokinetic profiles in mice. ABCG2-IN-2 can be used for the research of tumor multidrug resistance (MDR) and erythropoietic protoporphyria (EPP) .
Cat. No.: HY-155652
CAS No.: 2559759-40-7
ABCG2-IN-1 (compound K2), a Ko143 analog, is an orally active ABCG2 inhibitor with an IC50 of 0.13 μM. ABCG2-IN-1 has favorable oral pharmacokinetic profiles in mice .
Cat. No.: HY-170396
CAS No.: 2559759-63-4
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ABCG2-IN-4 (Compound K31) is an orally active inhibitor for ABCG2, which reduces the release of Protoporphyrin IX (PPIX) (HY-B1247) from erythrocytes into plasma, and prevents the reduces phototoxicity. ABCG2-IN-4 exhibits anti-inflammatory and antioxidant activity in mouse models .
Cat. No.: HY-RS00077
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ABCG2 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00078
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Abcg2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcg2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00079
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Abcg2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcg2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00080
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ABCG4 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCG4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00081
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ABCG5 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCG5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00082
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ABCG8 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCG8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24526
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Abcg8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcg8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-149469
CAS No.: 19056-75-8
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Cat. No.: HY-136450R
CAS No.: 100648-13-3
Synonyms: TCBZ-SO (Standard)
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Triclabendazole sulfoxide (Standard) is the analytical standard of Triclabendazole sulfoxide. This product is intended for research and analytical applications. Triclabendazole sulfoxide (TCBZ-SO) is an orally active ABCG2 inhibitor with antiparasitic activity. Triclabendazole sulfoxide inhibits ABCG2-mediated active efflux and ATPase activity. Triclabendazole sulfoxide increases the intracellular accumulation of Mitoxantrone (HY-13502). Triclabendazole sulfoxide reduces the apical-directed transepithelial transport of Nitrofurantoin and Danofloxacin, while increasing their basolateral-directed transepithelial transport. Triclabendazole sulfoxide elevates the plasma levels of sulfasalazine in wild-type mice. Triclabendazole sulfoxide decreases ABCG2-mediated secretion of Nitrofurantoin into milk in wild-type lactating mice. Triclabendazole sulfoxide can be used in the research of insecticidal agents and cancers such as breast cancer .
Cat. No.: HY-136450S
Synonyms: TCBZ-SO-d3
Cat. No.: HY-136450S1
Synonyms: TCBZ-SO-13C,d3
Cat. No.: HY-122416
CAS No.: 68236-11-3
Synonyms: Lonchocarpol A; Senegalensin
Category:
Erythrinasenegalensis DC. Metabolic Disease Plants Moraceae Flavonoids Leguminosae Humulus lupulus L. Flavonones Phenols Polyphenols Disease Research Fields Cancer
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Cat. No.: HY-121645
CAS No.: 19590-55-7
Synonyms: NSC103054
2,4-Dibromoestradiol (NSC103054) is a compound that is involved in the function of ABCG2 transporter.
Cat. No.: HY-168572
CAS No.: 2944457-11-6
MZ82, Ko 143 (HY-10010) derivative, is a ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor with the IC50 of ~23 nM. MZ82 not only shows greatly improved metabolic stability over Ko 143 (HY-10010) in liver microsomes but also in mice, and is able to penetrate into the brain .
Cat. No.: HY-N2651
CAS No.: 1268140-15-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
