2,4-Dibromoestradiol
2,4-Dibromoestradiol (NSC103054) is a compound that is involved in the function of ABCG2 transporter.
For research use only. We do not sell to patients.
- CAS No.: 19590-55-7
- Formula: C18H22Br2O2
- Molecular Weight:430.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | GI50 |
40 μM
Compound: 39
|
The In vitro cytotoxicity value corresponding to 50% growth inhibition against DU-145 (prostate) cell line.
The In vitro cytotoxicity value corresponding to 50% growth inhibition against DU-145 (prostate) cell line.
|
[PMID: 9240348] |
| HCT-116 | GI50 |
20 μM
Compound: 39
|
The In vitro cytotoxicity value is the concentration of the compound corresponding to 50% growth inhibition againstHCT-116 (colon) cell line.
The In vitro cytotoxicity value is the concentration of the compound corresponding to 50% growth inhibition againstHCT-116 (colon) cell line.
|
[PMID: 9240348] |
| MDA-MB-435 | GI50 |
27 μM
Compound: 39
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In vitro cytotoxicity value corresponding to 50% growth inhibition against MDA-MB-435 (breast) cell line.
In vitro cytotoxicity value corresponding to 50% growth inhibition against MDA-MB-435 (breast) cell line.
|
[PMID: 9240348] |
| OVCAR-3 | GI50 |
17 μM
Compound: 39
|
In vitro cytotoxicity value corresponding to 50% growth inhibition against OVCAR-3 (ovarian) cell line.
In vitro cytotoxicity value corresponding to 50% growth inhibition against OVCAR-3 (ovarian) cell line.
|
[PMID: 9240348] |
| Panel (Carcinoma cell lines) | GI50 |
25 μM
Compound: 39
|
Mean graph midpoint for growth inhibition of all human cancer cell lines
Mean graph midpoint for growth inhibition of all human cancer cell lines
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[PMID: 9240348] |
| SF-539 | GI50 |
21 μM
Compound: 39
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The In vitro cytotoxicity corresponding to 50% growth inhibition against SF-59 (central nervous system) cell line.
The In vitro cytotoxicity corresponding to 50% growth inhibition against SF-59 (central nervous system) cell line.
|
[PMID: 9240348] |
| SN12C | GI50 |
28 μM
Compound: 39
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In vitro cytotoxicity value corresponding to 50% growth inhibition against SN12C (renal) cell line.
In vitro cytotoxicity value corresponding to 50% growth inhibition against SN12C (renal) cell line.
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[PMID: 9240348] |
| UACC-62 | GI50 |
17 μM
Compound: 39
|
In vitro cytotoxicity value corresponding to 50% growth inhibition against UACC-62(melanoma) cell line.
In vitro cytotoxicity value corresponding to 50% growth inhibition against UACC-62(melanoma) cell line.
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[PMID: 9240348] |
Chemical Information
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CAS No. 19590-55-7
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Molecular Weight 430.17
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Formula C18H22Br2O2
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SMILES
C[C@]12CC[C@@]3([H])[C@@]([C@]1([H])CC[C@@H]2O)([H])CCC4=C(C(O)=C(C=C34)Br)Br
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Synonyms
NSC103054
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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