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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
97 Results for "
CD3 T cells
" in MedChemExpress (MCE) Product Catalog:
Products (97)
97 Results for "CD3 T cells" in MCE Product Catalog:
Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909
Cat. No.: HY-P99910
CAS No.: 1679391-73-1
Synonyms: AMG-330
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PROTAC PD-1/PD-L1 degrader-1, a PD-1/PD-L1 PROTAC based on Cereblon E3 ligand, inhibits PD-1/PD-L1 interaction with an IC50 of 39.2 nM. PROTAC PD-1/PD-L1 degrader-1 significantly restores the immunity repressed in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells. PROTAC PD-1/PD-L1 degrader-1 moderately reduces the protein levels of PD-L1 in a lysosome-dependent manner .
Cat. No.: HY-P99562
CAS No.: 2148354-90-7
Synonyms: XmAb-18087
Cat. No.: HY-P990802
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Cat. No.: HY-P990104
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Cat. No.: HY-P991490
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Cat. No.: HY-P99523
CAS No.: 2413453-53-7
Synonyms: AMG 199
Cat. No.: HY-P99390
CAS No.: 2044679-53-8
Synonyms: MCLA 117
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Cat. No.: HY-P990785
CAS No.: 2490552-52-6
Synonyms: ABBV-383; TNB 383B
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Cat. No.: HY-P99916
CAS No.: 2449199-61-3
Synonyms: AMG-427
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Cat. No.: HY-P99345
CAS No.: 2022215-59-2
Synonyms: TSR-042; ANB-011; WBP-285
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Cat. No.: HY-P990095
CAS No.: 2408319-33-3
Synonyms: REGN5459
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Cat. No.: HY-P99776
CAS No.: 2138442-31-4
Synonyms: XmAb-13676
Plamotamab (XmAb-13676) is a human bispecific antibody (bsAb) that binds CD3 and CD20. Plamotamab recruits cytotoxic T cells to kill CD20 + expressing tumor cells. Plamotamab induces a mild hematologic reaction (MR), and results in tumor regression in vivo .
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PKC-theta inhibitor 1 is an orally active and selective ATP-competitive inhibitor of Protein Kinase Cθ (PKCθ), with a Ki value of 6 nM. PKC-theta inhibitor 1 inhibits T-cell-mediated inflammatory responses by suppressing the release of proinflammatory cytokines (IL-2 IC50 = 0.21 μM in anti-CD3/CD28-stimulated PBMCs; IL-17 IC50 = 1 μM in CD3/CD28-stimulated Th17 cells) PKC-theta inhibitor 1 significantly reduces symptoms in mice with ongoing experimental autoimmune encephalomyelitis (EAE). PKC-theta inhibitor 1 can be used for the study of T-cell-mediated inflammatory diseases such as multiple sclerosis .
Cat. No.: HY-P99914
CAS No.: 2559704-23-1
Synonyms: GNC-038
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Cat. No.: HY-P991055
CAS No.: 2649379-96-2
Synonyms: RG-6234; RO-7425781
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Cat. No.: HY-P99757
CAS No.: 2278244-14-5
Synonyms: Hu3F8-BsAb
Cat. No.: HY-P990865
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KRM-III is an orally active TCR inhibitor and NFAT inhibitor with an IC50 of 5 μM against NFAT. KRM-III has no effect on the activation of nuclear factor-κB. KRM-III inhibits T cell proliferation induced by T cell antigen receptor stimulation. KRM-III abrogates anti-CD3 antibody-induced cell activation in vivo. KRM-III reduces paw pad swelling in delayed-type hypersensitivity induced by Bovine serum albumin (HY-D0842). KRM-III alleviates the severity of experimental autoimmune encephalomyelitis (EAE) in mice. KRM-III can be used in studies related to experimental autoimmune encephalomyelitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
