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Vonsetamig

(Synonyms: REGN5459)
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Vonsetamig (REGN5459) is a human bispecific antibody targeting BCMA and CD3. Vonsetamig triggers T-cell activation, induces plasma cell depletion, and triggers low-level cytokine release. Vonsetamig can be used for the research of relapsed/refractory multiple myeloma.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 95.00%
  • CAS. Nr.: 2408319-33-3
  • Molecular Weight:145.68 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vonsetamig
  • Experimental Validation Results for Vonsetamig
  • Experimental Validation Results for Vonsetamig
  • Experimental Validation Results for Vonsetamig
  • Vonsetamig Chemical Structure
    Vonsetamig Chemical Structure
CAS. Nr.: 2408319-33-3
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Vonsetamig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1X106 Raji cells with Vonsetamig (HY-P990095, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Vonsetamig (HY-P990095, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Serum BCMA/TNFRSF17 Trimer Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78071) on NTA biosensor, can bind Vonsetamig with an affinity constant of 2.585E-11 M as determined in BLI assay.

  • Vonsetamig Chemical Structure
    1/16
  • Vonsetamig
  • Flow cytometric analysis of 1X106 Raji cells with Vonsetamig (HY-P990095, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Flow cytometric analysis of 1X106 Jurkat cells with Vonsetamig (HY-P990095, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Serum BCMA/TNFRSF17 Trimer Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78071) on NTA biosensor, can bind Vonsetamig with an affinity constant of 2.585E-11 M as determined in BLI assay.