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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
114 Results for "
HCV replication
" in MedChemExpress (MCE) Product Catalog:
Products (114)
114 Results for "HCV replication" in MCE Product Catalog:
Cat. No.: HY-W128400
CAS No.: 123402-21-1
Target:
Research Areas:
3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA .
Cat. No.: HY-19558
CAS No.: 1036915-08-8
Target:
Research Areas:
IDX184 is a potent and orally bioavailable inhibitor of HCV replication. IDX184 potently inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3 nM) .
Cat. No.: HY-W011834S
CAS No.: 2653209-08-4
Cat. No.: HY-W555382
CAS No.: 55396-45-7
Synonyms: 2-Nonylquinolin-4(1H)-one
Category:
Alkaloids Ketones, Aldehydes, Acids Ruta graveolens Linn. Rutaceae Quinoline Alkaloids Plants
Target:
Cat. No.: HY-17470R
CAS No.: 50924-49-7
Synonyms: NSC 289637 (Standard); HE 69 (Standard)
Category:
Target:
Cat. No.: HY-132600A
Purity: 95.38%
Synonyms: Temavirsen sodium
RG-101 sodium is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication .
Cat. No.: HY-100603A
CAS No.: 1384097-27-1
(S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα). (S)-GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα, PI3Kβ and PI3Kδ with pIC50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model .
Cat. No.: HY-N8188
CAS No.: 117824-04-1
Target:
Cat. No.: HY-I0515
CAS No.: 1496552-51-2
Sofosbuvir impurity K, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
Cat. No.: HY-132600
CAS No.: 1929655-04-8
Synonyms: Temavirsen
RG-101 is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication .
Cat. No.: HY-15591
CAS No.: 1204416-97-6
TMC647055 is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication. TMC647055 has potent HCV combine activity with an IC50 value of 82 nM. TMC647055 can be used for the research of Hepatitis C virus (HCV) .
Target:
Research Areas:
Sofosbuvir impurity C is an impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
Cat. No.: HY-15005S
CAS No.: 2070009-25-3
Synonyms: PSI-7977-13C,d3; GS-7977-13C,d3
Cat. No.: HY-19512
CAS No.: 870142-71-5
Synonyms: GS9132
Target:
Research Areas:
ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.
Target:
Research Areas:
GS-6620 is potent and selective HCV inhibitor. GS-6620 inhibits HCV replication in genotype 1-6 subgenomic replicons and genotype 2a infectious virus, with EC50 values of 0.048-0.68 μM. GS-6620 can be used for the researches of infection and inflammation, such as Hepatitis C Virus (HCV) .
Cat. No.: HY-10241A
CAS No.: 1241946-89-3
Synonyms: TMC435 sodium; TMC435350 sodium
Target:
Research Areas:
Simeprevir (TMC435; TMC435350) sodium is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir sodium inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir sodium also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir sodium inhibits the main protease (M pro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses .
Cat. No.: HY-15005C
CAS No.: 1496552-16-9
Sofosbuvir impurity A, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
