(S)-GSK-F1
Based on 1 Customer Validation
(S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα). (S)-GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα, PI3Kβ and PI3Kδ with pIC50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 1384097-27-1
- Formula: C27H18F5N5O4S
- Molecular Weight:603.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI4KIIIα 8.3 (pIC50) |
PI4KIIIβ 6.0 (pIC50) |
PI3Kα 5.6 (pIC50) |
PI3Kδ 5.6 (pIC50) |
PI3Kβ 5.1 (pIC50) |
Chemical Information
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CAS No. 1384097-27-1
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Appearance Solid
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Molecular Weight 603.52
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Formula C27H18F5N5O4S
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Color White to off-white
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SMILES
O=C1C2=C(N=C(N1C3=CC=CC=C3C(F)(F)F)N)C=CC(C4=CC(S(=O)(NC5=CC=C(C=C5F)F)=O)=C(OC)N=C4)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-GSK-F1 Related Classifications
HY-100603A Related Classifications
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