123402-21-1
Chemical Structure
3′-Deoxy-3′-fluoroguanosine
- CAS No.: 123402-21-1
- Formula:C10H12FN5O4
- Molecular Weight:285.23
IUPAC Name: 2-amino-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: VDOWHLFGBWKXJC-DXTOWSMRSA-N
SMILES: NC(NC1=O)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](F)[C@H]3O
Biological Activity: 3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA[1].
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3′-Deoxy-3′-fluoroguanosine | 3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA. | |||||||||||||||||||||
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Keywords