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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
generalized
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "generalized" in MCE Product Catalog:
Cat. No.: HY-123681
CAS No.: 98164-11-5
Target:
Research Areas:
R 57720 is an antiepileptic agent that exhibits dose-dependent anticonvulsant activity across multiple postnatal rat age groups. R 57720 inhibits severe generalized tonic-clonic seizures induced by Pentylenetetrazol. R 57720 can be used for epilepsy research .
Cat. No.: HY-B1115S
CAS No.: 1216761-39-5
Target:
Research Areas:
N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures.
Cat. No.: HY-19686A
CAS No.: 92589-98-5
Synonyms: TVX Q 7821
Target:
Research Areas:
Ipsapirone hydrochloride (TVX Q 7821) is an anxiolytic compound and a 5-HT1A receptor partial agonist. Ipsapirone hydrochloride (TVX Q 7821) also exhibits 5-HT1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT2 and the α1-adrenergic function .
Cat. No.: HY-B0161AR
CAS No.: 136434-34-9
Synonyms: (S)-Duloxetine hydrochloride (Standard); LY-248686 hydrochloride (Standard)
Research Areas:
Duloxetine (hydrochloride) (Standard) is the analytical standard of Duloxetine (hydrochloride). This product is intended for research and analytical applications. Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .
Cat. No.: HY-B0161S3
CAS No.: 1276197-53-5
Synonyms: (S)-Duloxetine-d5 oxalate; LY248686-d5 oxalate
Cat. No.: HY-10420
CAS No.: 89592-45-0
Target:
Research Areas:
ZK-93426 is a benzodiazepine receptor antagonist. ZK-93426 does not alter the dogs' motility but induces generalized myoclonic jerks and tonic-clonic seizures. ZK-93426 can be used to study the mechanism of withdrawal reactions in the state of benzodiazepine dependence .
Cat. No.: HY-B0161AS1
Synonyms: (S)-Duloxetine-d7 hydrochloride; LY248686-d7 hydrochloride
Cat. No.: HY-17447SA
CAS No.: 107077-98-5
Synonyms: SKF 385-d5 hydrochloride
Cat. No.: HY-136487
CAS No.: 220747-81-9
Synonyms: Bu N-oxide
Target:
Research Areas:
Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone (HY-B1115A). Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research .
Cat. No.: HY-145487A
Target:
Research Areas:
5-Hydroxy-6-methoxy (S)-duloxetine maleate is an orally active and brain-penetrant serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with antidepressant and analgesic activities. 5-Hydroxy-6-methoxy (S)-duloxetine maleate is promising for research of psychiatric and neurological disorders such as depression, diabetic neuropathic pain, generalized anxiety disorder, and fibromyalgia .
Cat. No.: HY-W008270R
CAS No.: 497-23-4
Synonyms: γ-Crotonolactone (Standard)
Category:
Cat. No.: HY-B1496R
CAS No.: 13492-01-8
Synonyms: SKF 385 hemisulfate (Standard)
Research Areas:
Tranylcypromine (hemisulfate) (Standard) is the analytical standard of Tranylcypromine (hemisulfate). This product is intended for research and analytical applications. Tranylcypromine (SKF 385) hemisulfate is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Tranylcypromine has antidepressant effects .
Cat. No.: HY-W707539
Synonyms: RWJ-333369-d215N
Cat. No.: HY-120045A
CAS No.: 115904-74-0
Target:
Research Areas:
DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spiradoline-appropriate selection when administered SC, but showed a partial generalized response to spiradoline when administered IP or PO. The 5-hydroxy-desmethoxy metabolite of DuP 747 induced selection of the saline-appropriate lever only. The effects of DuP 747 suggest that its metabolites may play a major role in the similar responses to spiradoline after IP and PO administration .
Cat. No.: HY-19682
CAS No.: 68576-86-3
Target:
Research Areas:
Enciprazine is an orally active non-benzodiazepine anxiolytic. Enciprazine acts as an agonist of 5-HT1A receptor (5-HT1AR) and an antagonist of α1-adrenergic receptor (α1-adrenergic receptor) . Enciprazine induces drug-related electroencephalogram changes by reducing the average power of δ waves and θ waves, and increasing the average power of α waves and fast β waves. Enciprazine exhibits anti-aggressive activity, with only weak sedative and ataxic effects. Enciprazine regulates plasma corticosterone levels and activates the hypothalamic-pituitary-adrenal axis. Enciprazine can be used in research related to anxiety disorders, generalized anxiety syndrome and psychosis .
Cat. No.: HY-111124
CAS No.: 923932-43-8
Synonyms: BRL29060-d2
Cat. No.: HY-122272S
CAS No.: 923932-45-0
Synonyms: BRL29060-d4
Cat. No.: HY-122272S2
CAS No.: 1435728-63-4
Synonyms: BRL29060-d6-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
