Buspirone N-oxide
Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone (HY-B1115A). Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research.
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- CAS No.: 220747-81-9
- Formule: C21H31N5O3
- Masse moléculaire:401.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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5-HT1A Receptor |
Chemical Information
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CAS No. 220747-81-9
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Masse moléculaire 401.50
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Formule C21H31N5O3
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SMILES
O=C(N(CCCC[N+]1([O-])CCN(C2=NC=CC=N2)CC1)C(C3)=O)CC43CCCC4
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Synonyms
Bu N-oxide
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Zhu M, et al. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes. Drug Metab Dispos. 2005 Apr;33(4):500-7. [Content Brief]
[2]. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11(1):6094. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Buspirone N-oxide Related Classifications
HY-136487 Related Classifications
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