Buspirone N-oxide
Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone (HY-B1115A). Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. Buspirone is an anxiolytic agent, and can be used for the generalized anxiety disorder research.
For research use only. We do not sell to patients.
- CAS No.: 220747-81-9
- Formula: C21H31N5O3
- Molecular Weight:401.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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5-HT1A Receptor |
Chemical Information
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CAS No. 220747-81-9
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Molecular Weight 401.50
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Formula C21H31N5O3
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SMILES
O=C(N(CCCC[N+]1([O-])CCN(C2=NC=CC=N2)CC1)C(C3)=O)CC43CCCC4
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Synonyms
Bu N-oxide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhu M, et al. Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes. Drug Metab Dispos. 2005 Apr;33(4):500-7. [Content Brief]
[2]. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11(1):6094. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Buspirone N-oxide Related Classifications
HY-136487 Related Classifications
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