136434-34-9
136434-34-9
Chemical Structure
Duloxetine hydrochloride
Synonym(s): (S)-Duloxetine hydrochloride; LY-248686 hydrochloride
- CAS No.: 136434-34-9
- Formula:C18H20ClNOS
- Molecular Weight:333.88
IUPAC Name: (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine hydrochloride
InChIKey: BFFSMCNJSOPUAY-LMOVPXPDSA-N
SMILES: CNCC[C@H](OC1=CC=CC2=C1C=CC=C2)C3=CC=CS3.[H]Cl
Biological Activity: Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].
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Duloxetine hydrochloride | 99.97% | Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | ||||||||||||||||||||
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Duloxetine hydrochloride (Standard) | ≥98% | Duloxetine (hydrochloride) (Standard) is the analytical standard of Duloxetine (hydrochloride). This product is intended for research and analytical applications. Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | ||||||||||||||||||||
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Duloxetine-d7 hydrochloride | Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | |||||||||||||||||||||
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Duloxetine-d3 hydrochloride | Duloxetine-d3 (hydrochloride) is a deuterium labeled Duloxetine hydrochloride. Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | |||||||||||||||||||||
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References
- [1]. Redrobe JP, et al. Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity. Psychopharmacology (Berl). 1998 Jul;138(1):1-8. [Content Brief]
- [2]. Deecher DC, et al. Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor. J Pharmacol Exp Ther. 2006 Aug;318(2):657-65. Epub 2006 May 4. [Content Brief]
