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Cat. No.: HY-Z13521

Duloxetine impurity 13

Duloxetine impurity 13 is an impurity of Duloxetine.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 178273-35-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Duloxetine impurity 13 is an impurity of Duloxetine.

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	>10 μM Compound: (S)-10b, (S)-Norduloxetine	Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cells Inhibition of [3H]DA reuptake at human DAT expressed in HEK293 cells	[PMID: 19740668]
HEK293	IC₅₀	25.6 nM Compound: (S)-10b, (S)-Norduloxetine	Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cells Inhibition of [3H]5HT reuptake at human SERT expressed in HEK293 cells	[PMID: 19740668]
HEK293	IC₅₀	445 nM Compound: (S)-10b, (S)-Norduloxetine	Inhibition of [3H]NE reuptake at human NET expressed in HEK cells Inhibition of [3H]NE reuptake at human NET expressed in HEK cells	[PMID: 19740668]

CAS No. 178273-35-3
Molecular Weight 283.39
Formula C₁₇H₁₇NOS
SMILES

O([C@@H](CCN)C1=CC=CS1)C=2C3=C(C=CC2)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.