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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
270 Results for "
sustained
" in MedChemExpress (MCE) Product Catalog:
Products (270)
270 Results for "sustained" in MCE Product Catalog:
Cat. No.: HY-P10341
CAS No.: 1345835-12-2
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Cat. No.: HY-N2269
CAS No.: 87932-34-1
Synonyms: 4-Hydroxyphenethyl anisate
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Monophenols Metabolic Disease Phenols Plants Umbelliferae Kleinia odora (Forssk.) DC. Disease Research Fields
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Cat. No.: HY-148281
CAS No.: 2418022-85-0
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TMX-2164 is a potent, irreversible B-cell lymphoma 6 (BCL6) inhibitor with an IC50 value of 152 nM. TMX-2164 displays sustained target engagement and antiproliferative activity in cells .
Cat. No.: HY-163684
CAS No.: 2243483-63-6
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Zoracopan is a selective complement factor D (CFD) inhibitor. When administered systemically (orally or intravenously), Zoracopan accumulates and is sustained-released in ocular tissues, primarily in the choroid-retinal pigment epithelium (C-RPE) and/or iridociliary body (I-CB) .
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Cat. No.: HY-P99790
CAS No.: 147191-91-1
Synonyms: CEN 000029; cM-T412
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Cat. No.: HY-117985
CAS No.: 1222102-29-5
Synonyms: DA-1229
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Evogliptin (DA-1229) is an orally active DPP4 inhibitor with significant and sustained hypoglycaemic effects in mouse models. Evogliptin also inhibits the production of inflammatory and fibrotic signals in hepatocytes by inducing autophagy. Evogliptin can be used in studies of type 2 diabetes, osteoporosis, renal impairment and chronic liver inflammation .
Cat. No.: HY-Y0850U2
CAS No.: 9002-89-5
Synonyms: Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)
Cat. No.: HY-P10895
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Synonyms: LY582563; MCC-478
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect .
Cat. No.: HY-P5163
CAS No.: 2843557-76-4
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Cat. No.: HY-179131
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TN-783 is an orally active, brain-penetrant NLRP3 (IC50 = 19.3 nM) inhibitor. TN-783 enhances the effects of the GLP-1 receptor agonist semaglutide. TN-783 requires sustained targeted action, not permanent metabolic remodeling. TN-783 can be used for the study of obesity .
Cat. No.: HY-N0322GL
CAS No.: 57-88-5
Cat. No.: HY-176783
CAS No.: 3080315-83-6
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GNE-5152 is an orthosteric SARM1 base-exchange (BE) inhibitor. GNE-5152 sustainably activates SARM1 at subinhibitory concentrations under mildly activating conditions, and this synergistic adverse effect increases NAD consumption, induces axon degradation and neurodegeneration and releases neurofilament-light (NfL) in cortical neurons. GNE-5152 can be used for neurodegenerative diseases research .
Cat. No.: HY-W013807R
CAS No.: 109-43-3
Synonyms: Dibutyl decanedioate (Standard)
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Dibutyl sebacate (Standard) (Dibutyl decanedioate (Standard)) is the analytical standard of Dibutyl sebacate (HY-W013807). This product is intended for research and analytical applications. Dibutyl sebacate (Dibutyl decanedioate) is a PVC eco-friendly plasticizer. Dibutyl sebacate plasticizes Eudragit RS 30D, reducing the glass transition temperature and minimum film-forming temperature for sustained-release coatings, with no aging effect .
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SK609 hydrochloride is a dopamine D3 receptor (D3R) selective agonist with an EC50 of 1109 nM. SK609 hydrochloride has the potential for parkinson research .
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OSMI-3 (Compound 2b) is a potent, long-lasting, and cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-3 increases detained intron splicing in cells .
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Ethyl acrylate-methyl methacrylate copolymer can be used as an excipient, such as sustained-release coating materials, matrix sustained-release tablet binders and retarders. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
Cat. No.: HY-N16475
CAS No.: 149092-01-3
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Cat. No.: HY-16634
CAS No.: 1303609-30-4
MI-888 (TFA) is an orally active MDM2-p53 interaction inhibitor with a Ki of 0.44 nM. MI-888 (TFA) can achieve rapid, complete, and sustained tumor regression in a xenograft mouse model of cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
