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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
132 Results for "
Acinetobacter
" in MedChemExpress (MCE) Product Catalog:
Products (132)
132 Results for "Acinetobacter" in MCE Product Catalog:
Cat. No.: HY-B0117R
CAS No.: 220620-09-7
Synonyms: GAR-936 (Standard)
Category:
Cat. No.: HY-B0317F
CAS No.: 246852-07-3
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Amlodipine hydrochloride is a biologically active drug used to lower blood pressure and prevent chest pain. Amlodipine hydrochloride has shown synergistic effects with antimicrobial drugs in in vitro studies, especially against carbene peptide-resistant Acinetobacter baumannii. Amlodipine hydrochloride can be used in combination with other antibiotics to enhance the inhibitory effect against resistant bacteria. The use of amlodipine hydrochloride helps reduce the dosage requirements of the drug, reduce toxic effects, and delay the emergence of drug resistance .
Cat. No.: HY-122699
CAS No.: 247115-03-3
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LN-1-255 sodium is a β-lactamase inhibitor. LN-1-255 sodium has broad-spectrum inhibitory effect on type D carbapenemases (CHDLs) with an IC50 for OXA-48 of 3 nM, and it also has strong activity against OXA-23, OXA-24/40, etc. LN-1-255 sodium combined with carbapenem antibiotics has a synergistic effect. LN-1-255 sodium can be used to study the bacterial resistance crisis caused by CHDLs .
Cat. No.: HY-P11004
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Cat. No.: HY-121195
CAS No.: 63469-19-2
Synonyms: PC-904
Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
Cat. No.: HY-P11250
Target:
Bacterial NO Synthase Interleukin Related Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) ERK JNK p38 MAPK
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Cat. No.: HY-103251R
CAS No.: 1312473-63-4
Synonyms: LpxC-4 (Standard)
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Cefalonium (dihydrate) (Standard) is the analytical standard of Cefalonium (dihydrate). This product is intended for research and analytical applications. Cefalonium dihydrate is a cephalosporin antibiotic. Cefalonium (dihydrate) is effective against Staphylococcus aureus. Cefalonium (dihydrate) has anti-inflammatory and antibacterial activities .
Cat. No.: HY-162839
CAS No.: 3018085-89-4
Cerastecin D (compound 1) is an antibacterial agent. Cerastecin D shows inhibition on Acinetobacter baumannii ATCC19606 with MITC95 values of 165 nM .
Cat. No.: HY-168955
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Antibacterial agent 269 (3.8) is an inhibitor of AdeG Efflux Pumps in Acinetobacter baumannii .
Cat. No.: HY-178384
Antibacterial agent 294 is an antibacterial agent. Antibacterial agent 294 shows antibacterial effect against carbapenem-resistant Acinetobacter baumannii (CRAB) with a MIC of 0.5 μg/mL. Antibacterial agent 294 can be used for the research of infection .
Cat. No.: HY-124789R
CAS No.: 52535-76-9
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TBT1 (Standard) is the analytical standard of TBT1. This product is intended for research and analytical applications. TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM[1].
Cat. No.: HY-N15678
CAS No.: 52940-12-2
Synonyms: 1,3,6,8-THAQ
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Cat. No.: HY-P10700
CAS No.: 2097285-98-6
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Cat. No.: HY-155007
Purity: 99.77%
DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 < 10 nM) and broad-spectrum antibacterial activity against pathogens belonging to the ESKAPE group, with the minimum inhibitory concentration < 0.03 μg/mL for most Gram-positive strains and 4–16 μg/mL against Gram-negative E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection .
Cat. No.: HY-P0135
CAS No.: 19431-21-1
Penta lysine is an antimicrobial peptide. Penta lysine inhibits the growth of Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus and Bacillus subtilis) as well as Gram-negative bacteria (including Escherichia coli, Acinetobacter baumannii and Pseudomonas aeruginosa). Penta lysine induces hemolysis in human red blood cells. Penta lysine can be used in the research of bacterial infections (including MRSA and Pseudomonas aeruginosa infections) .
Cat. No.: HY-163473
CAS No.: 20193-94-6
IITR08367 is a potent effector pump Acinetobacter baumannii Fosfomycin Efflux pump (AbaF) inhibitor for enhancing the antimicrobial activity of Fosfomycin (HY-B1075A) against Acinetobacter baumannii. IITR08367 acts by interfering with Fosfomycin/H + reverse transporter activity. .
Cat. No.: HY-N16389
CAS No.: 457893-80-0
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Cat. No.: HY-B0334R
CAS No.: 68373-14-8
Synonyms: CP45899 (Standard)
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Sulbactam (Standard) is the analytical standard of Sulbactam. This product is intended for research and analytical applications. Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex .
Cat. No.: HY-P10402
CAS No.: 939963-76-5
Cat. No.: HY-144387
CAS No.: 3033367-64-2
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ient S. Tm and hyperpermeable Escherichia coli. The potencies against WT strains of E. coli, Acinetobacter baumannii, and Burkholderia cenocepacia are also improved considerably (up to >128-fold) with the outer-membrane permeabi
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
