BMAP 28 (bovine)
BMAP 28, bovine is an antibacterial peptide. BMAP 28, bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28, bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28, bovine induces apoptosis through depolarization of mitochondrial membrane potential.
For research use only. We do not sell to patients.
- CAS No.: 939963-76-5
- Formula: C147H252N44O31
- Molecular Weight:3131.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 939963-76-5
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Molecular Weight 3131.85
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Formula C147H252N44O31
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Sequence
Gly-Gly-Leu-Arg-Ser-Leu-Gly-Arg-Lys-Ile-Leu-Arg-Ala-Trp-Lys-Lys-Tyr-Gly-Pro-Ile-Ile-Val-Pro-Ile-Ile-Arg-Ile-Gly
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Sequence Shortening
GGLRSLGRKILRAWKKYGPIIVPIIRIG
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Brogden KA, et al., Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents. 2003 Nov;22(5):465-78. [Content Brief]
[2]. Guo Y, et al., A bovine myeloid antimicrobial peptide (BMAP-28) and its analogs kill pan-drug-resistant Acinetobacter baumannii by interacting with outer membrane protein A (OmpA). Medicine (Baltimore). 2018 Oct;97(42):e12832. [Content Brief]
[3]. Risso A, et al., BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22(6):1926-35. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)