148 Results for "

CD40

" in MedChemExpress (MCE) Product Catalog:
Products (148)

148 Results for "CD40" in MCE Product Catalog:

Cat. No.: HY-P991557

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

ABI793 is a human IgG1 anti-human CD154 (CD40 ligand) monoclonal antibody. ABI793 inhibits immune response by blocking the CD154-CD40 (IC50 = 75 nM) signaling pathway. ABI793 effectively prevents kidney transplant rejection. ABI793 can be used for research on immunological rejection .
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Cat. No.: HY-P99663
CAS No.: 2568264-76-4
Synonyms: AMG-994

Target:  

TNF Receptor

Research Areas:  

Cancer

Inezetamab is a bispecific anti-CD40 and anti-MSLN IgG1 monoclonal antibody .
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Cat. No.: HY-P991510

Target:  

TNF Receptor

Research Areas:  

Cancer

CDX-1140 is a fully human IgG monoclonal antibody and CD40 agonist, with a Kd value of 0.01 nM against human targets. The epitope of CDX-1140 locates at CD40 CRD1 and avoids the CD40L binding site. It activates DCs and B cells, drives NF-κB reporter gene activation, exhibits agonist activity independent of FcR cross-linking, and shows a synergistic effect with recombinant CD40L . CDX-1140 does not induce systemic cytokine release, exerts direct and immune-mediated anti-tumor activity in tumor xenografts, and has favorable safety profiles. When used as a local vaccine adjuvant in combination with 6MHP+mBRAF+poly-ICLC, CDX-1140 increases the number of DC-LAMP + DCs and induces Th1 CD4 + responses in high-risk melanoma. CDX-1140 can be used in studies related to B-cell lymphoma, bladder cancer and high-risk melanoma .
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Cat. No.: HY-P991126
CAS No.: 3014361-59-9
Synonyms: YH003

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Ciltistotug is a monoclonal antibody targeting human CD40 (TNFRSF5). Ciltistotug activates immune cells after binding to CD40, exerting immunostimulatory and antitumor activities. Ciltistotug is promising for research of cancer immunotherapy .
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Cat. No.: HY-P991556

Target:  

TNF Receptor

Research Areas:  

Cancer

TQB2916 is a humanized IgG2 monoclonal antibody agonist targeting CD40. TQB2916 has a significant antitumor activity with CD40 occupancy and immune activation. TQB2916 can be used for advanced solid tumors and lymphomas research .
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Cat. No.: HY-P991666

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

BMS-986090 is a humanized monoclonal antibody antagonist targeting CD40. BMS-986090 is promising for research of autoimmune diseases such as systemic lupus erythematosus (SLE) and focal segmental glomerulosclerosis (FSGS) .
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Cat. No.: HY-143410
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 16 (compound 14), a peptidomimetic, shows potent anti-inflammatory activity. Anti-inflammatory agent 16 reduces TNFα, NO, CD40 and CD86 expression level .
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Cat. No.: HY-P990044
CAS No.: 2642171-59-1
Synonyms: LVGN-7409

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Dalnicastobart (LVGN-7409) is a human IgG1κ antibody targeting CD40/TNFRSF5 .
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Cat. No.: HY-P990270

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse CD40L/CD154. Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) is a chimeric version of the original MR-1 antibody (HY-P990134). The variable domain sequences are identical to the original MR-1 but the constant region sequences have been switched from Armenian hamster IgG to mouse IgG1. Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) blocks CD40/CD40L signaling. Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) can be used for researches of cancer, inflammation and immunology.
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Cat. No.: HY-D1124
CAS No.: 3564-15-6
Mordant brown 1, a naphthalenesulphonic acid derivative, is an azo dye. Mordant brown 1 is also an effective and specific inhibitor of CD40-CD154 costimulatory protein-protein interaction .
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Cat. No.: HY-P10937
CAS No.: 2891466-35-4
Target:  

Aquaporin

Research Areas:  

Inflammation/Immunology

AQP4 (205-215) is a fragment of Aquaporin-4 (AQP4). AQP4 is a neuromyelitis optica autoantigen that is upregulated and presented in B cells after engagement of CD40. AQP4 is associated with autoimmune inflammatory diseases of the central nervous system (CNS), neuromyelitis optica (NMO) .
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Cat. No.: HY-174737
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CD40LG mRNA encodes the human CD40 ligand (CD40LG) protein, a protein that is expressed on the surface of T cells. CD40LG regulates B cell function by engaging CD40 on the B cell surface.
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Cat. No.: HY-P990527

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-TNFRSF5/CD40 Antibody is a CHO-expressed human antibody that targets TNFRSF5/CD40. The Anti-TNFRSF5/CD40 Antibody contains a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. For the isotype control of Anti-TNFRSF5/CD40 Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P78612
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Rabbit
Source:  
HEK293
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Cat. No.: HY-P7837
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P74296
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P75412
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P75413
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P72910
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72911
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40; B-Cell Surface Antigen CD40; Prev. TNFRSF5; B Cell Surface Antigen CD40; Bp50; B Cell-Associated Molecule; Tumor Necrosis Factor Receptor Superfamily Member 5; CD40 Antigen; CD40L Receptor; CDW40; P50; CDw40; CD40 Molecule, TNF Receptor Superfamily
Species:  
Mouse
Source:  
HEK293
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