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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
90 Results for "
catechol
" in MedChemExpress (MCE) Product Catalog:
Products (90)
90 Results for "catechol" in MCE Product Catalog:
Cat. No.: HY-106405R
CAS No.: 274925-86-9
Synonyms: BIA 3-202 (Standard)
Target:
Research Areas:
Nebicapone (Standard) is the analytical standard of Nebicapone. This product is intended for research and analytical applications. Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
Cat. No.: HY-N10771
CAS No.: 2244560-40-3
Category:
Flavonoids Gramineae Terpenoids Morus nigra Linn. Diterpenoids Plants Moraceae Saccharum officinarum Other Flavonoids
Target:
Cat. No.: HY-W272201
CAS No.: 635-67-6
Target:
Research Areas:
Catechol diacetate (Compound 15) is a carbonic anhydrase (CA) inhibitor. Catechol diacetate is promising for research of glaucoma, epilepsy, edema, and cancer .
Cat. No.: HY-100959R
CAS No.: 7659-29-2
Synonyms: OR-486 (Standard); 3,5-Dinitropyrocatechol (Standard)
Target:
3,5-Dinitrocatechol (Standard) (OR-486 (Standard); 3,5-Dinitropyrocatechol (Standard)) is the analytical standard of 3,5-Dinitrocatechol (HY-100959). This product is intended for research and analytical applications. 3,5-Dinitrocatechol (OR-486) is an orally active, blood-brain barrier-permeable selective catechol-O-methyltransferase (COMT) inhibitor. 3,5-Dinitrocatechol can be used in research related to Parkinson's disease, pheochromocytoma and adult cataract .
Cat. No.: HY-162760
CAS No.: 2987884-27-3
Target:
Research Areas:
COMT-IN-1 (compound C12), a nitrophenolic analogue, is an orally active dopamine metabolic enzyme catechol-O-methyltransferase (COMT) inhibitor with IC50s of 0.37 μM, 95.58 μM and 58.82 μM for COMT, MAO-A and MAO-B, respectively. COMT-IN-1 exhibits chelation with a variety of metal ions. COMT-IN-1 exhibits good BBB permeability. COMT-IN-1 improves dopamine levels and ameliorates MPTP (HY-15608)-induced Parkinson's disease (PD) symptoms in mice .
Cat. No.: HY-W112564
CAS No.: 4918-98-3
Synonyms: catechol phosphate
2-Hydroxyphenyl dihydrogen phosphate (Catechol phosphate) is a metal-organic framework (MOF).
Cat. No.: HY-E70970
Target:
Research Areas:
Catechol-O-methyl Transferase, Porcine (EC 2.1.1.6) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine.
Cat. No.: HY-W747910A
CAS No.: 19971-73-4
Target:
Research Areas:
S584 dihydrochloride is a catechol metabolite of the oral-effective Piribedil (HY-12707), with anti-lipid peroxidation activity. S584 dihydrochloride significantly inhibits lipid peroxidation in rat synaptosomes under basal conditions and Fe³⁺ stimulation. S584 dihydrochloride significantly antagonizes the increase in thiobarbituric acid reactive substances (TBARS) in the brains of mice exposed to high oxygen and under normal air conditions .
Cat. No.: HY-N21616
CAS No.: 145194-15-6
Category:
Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Chamaecrista nomame(Siebold) H. Ohashi
Target:
Cat. No.: HY-P72149
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COMT; catechol-O-Methyltransferase Isoform; catechol-O-Methyltransferase; Testicular Tissue Protein Li 42; catechol O-Methyltransferase; HEL-S-98n; Epididymis Secretory Sperm Binding Protein Li 98n
Species:
Human
Source:
E. coli
Cat. No.: HY-P74230
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: COMT; catechol-O-Methyltransferase Isoform; catechol-O-Methyltransferase; Testicular Tissue Protein Li 42; catechol O-Methyltransferase; HEL-S-98n; Epididymis Secretory Sperm Binding Protein Li 98n
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-N17718
CAS No.: 83543-37-7
Synonyms: 3-[8'(Z), 11'(Z), 14'-Pentadecatrienyl] catechol
Target:
Cat. No.: HY-N13090
CAS No.: 34425-64-4
Category:
Target:
Cat. No.: HY-E71569
Target:
Research Areas:
2-Hydroxymuconate-6-semialdehyde dehydrogenase (EC 1.2.1.85): this substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2, catechol 2,3-dioxygenase), and is an intermediate in the bacterial degradation of several aromatic compounds.
Cat. No.: HY-E71570
Target:
Research Areas:
2-Hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) is involved in the degradation of catechols.
Cat. No.: HY-E71568
Target:
Research Areas:
2-Hydroxymuconate tautomerase (EC 5.3.2.6) involved in the meta-cleavage pathway for the degradation of phenols, modified phenols and catechols.
Cat. No.: HY-E71600
Target:
Research Areas:
2-Oxo-3-hexenedioate decarboxylase (EC 4.1.1.77) involved in the meta-cleavage pathway for the degradation of phenols, modified phenols and catechols.
Cat. No.: HY-W761397
CAS No.: 117568-28-2
Target:
Research Areas:
COMT-IN-3 is a competitive inhibitor of soluble catechol-O-methyltransferase (S-COMT). COMT-IN-3 coordinates with the Mg 2+ ion at the COMT active site via its catechol hydroxyl group, and its nitro group, as a strong electron-withdrawing substituent, further enhances the binding affinity. COMT-IN-3 interacts with the hydrophobic residues Trp38, Met40, and Trp143 at the back of the active site via its neutral nitrile tail, thereby competitively inhibiting COMT activity. COMT-IN-3 can be used in research related to Parkinson's disease .
Cat. No.: HY-B1473AR
CAS No.: 50-67-9
Synonyms: 5-Hydroxytryptamine (Standard); 5-HT (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
