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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
diffusion
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "diffusion" in MCE Product Catalog:
Cat. No.: HY-W040074
CAS No.: 23273-91-8
Synonyms: Diglycine hydrochloride hydrate; Gly-Gly (HCl H2O)
Cat. No.: HY-128443R
CAS No.: 122-19-0
Synonyms: BDMSAC (Standard)
Research Areas:
Benzyldimethylstearylammonium chloride (Standard) (BDMSAC (Standard)) is the analytical standard of Benzyldimethylstearylammonium chloride (HY-128443). This product is intended for research and analytical applications. Benzyldimethylstearylammonium chloride is a quaternary ammonium cationic surfactant and a mixed-type corrosion inhibitor. Benzyldimethylstearylammonium chloride adsorbs onto the surface of cold-rolled steel through a combined effect of physisorption and chemisorption, forming a hydrophobic protective barrier that blocks active sites and restricts the diffusion of corrosive media, while simultaneously inhibiting the anodic iron dissolution reaction and the cathodic hydrogen evolution reaction, and reducing the corrosion rate in acidic media. Benzyldimethylstearylammonium chloride is used in research related to various fields such as fungicides, wastewater treatment, and detergents .
Cat. No.: HY-B0396R
CAS No.: 161715-24-8
Synonyms: L084 (Standard)
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Tebipenem pivoxil (Standard) (L084 (Standard)) is the analytical standard of Tebipenem pivoxil (HY-B0396). This product is intended for research and analytical applications. Tebipenem pivoxil (L084 hydrobromide) is an orally active carbapenem Antibiotic. Tebipenem pivoxil acts as a substrate of OATP1A2 with high affinity for this transporter (Km = 41.1 μM) . Tebipenem pivoxil achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis .
Synonyms: 4-Des-dimethylaminotetracycline; 4-De(dimethylamino)-tc; CMT-1
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DDA-tetracycline is a tetracycline derivative (4-des-dimethylaminotetracycline, also called CMT-1) .DDA-tetracycline is subject to conflicting classification, with one source noting no definitive identity or classification, and specifying the abbreviation 'DDA' may refer to the disk diffusion agar method rather than the reagent itself .
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Cat. No.: HY-W587665
CAS No.: 2496-92-6
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Demeton-S sulfoxide is a systemic insecticide. When Demeton-S sulfoxide is topically applied to cotton stems, it is absorbed and transported to cotton leaves, whereas its penetration and diffusion capabilities are limited when it is topically applied to young lemon leaves .
Cat. No.: HY-D3485
CAS No.: 216854-76-1
Cat. No.: HY-118260
CAS No.: 130905-04-3
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Phendioxan is a compound with binding activity at the α(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved α(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding .
Cat. No.: HY-19688
CAS No.: 57695-04-2
Synonyms: WR 6026
Research Areas:
Sitamaquine (WR 6026) is an orally active Antileishmanial agent and Succinate dehydrogenase inhibitor. Sitamaquine accumulates in the acidocalcisomes of Leishmania, induces organelle alkalization, and crosses the plasma membrane of Leishmania via temperature- and energy-independent diffusion. Sitamaquine disrupts oxidative phosphorylation in Leishmania, induces mitochondrial depolarization, oxidative stress, elevated intracellular calcium, plasma membrane depolarization, and Apoptosis-like cell death. Sitamaquine can be used in the research of leishmaniasis .
Cat. No.: HY-D3196
CAS No.: 1198157-60-6
Cat. No.: HY-B0377A
CAS No.: 125193-62-6
Synonyms: MK-208 hydrochloride
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Famotidine hydrochloride (MK-208 hydrochloride) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine hydrochloride inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine hydrochloride scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine hydrochloride crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine hydrochloride reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine hydrochloride can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
Cat. No.: HY-D3240
CAS No.: 2375541-43-6
Cat. No.: HY-180784
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Hypoglycemic agent 4 (Compound 5b) is a tetrahydroacridine derivative with orally active hypoglycemic activity. Hypoglycemic agent 4 has a good binding affinity for the key diabetic targets: DPP-IV, SGLT1, and GLUT2. Hypoglycemic agent 4 can inhibit glucose diffusion. Hypoglycemic agent 4 can reduce fasting blood sugar in Streptozotocin (HY-13753)-induced diabetic rats and its effect is comparable to Gliclazide (HY-B0753). Hypoglycemic agent 4 can be used for research of type 2 diabetes .
Cat. No.: HY-D3047I
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Rhodamine B-Dextran (chloride) (MW 500000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 500000. Rhodamine B-Dextran (chloride) (MW 500000) is a fluorescent dye used to track the diffusion of macromolecules in ex vivo human skin. Rhodamine B-Dextran (chloride) (MW 500000) is delivered to skin layers via the Nanopatch microneedle array, which physically disrupts the stratum corneum and dermal-epidermal junction barriers to deposit the dye directly into epidermal and dermal regions; fluorescence is detected via multiphoton microscopy, and fluorescence intensity is assumed to be roughly proportional to dye concentration .
Cat. No.: HY-W583729
CAS No.: 26023-30-3
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DL-Poly (lactic acid) is a biodegradable poly (α-hydroxy acid) matrix and a coating material for controlled drug release. DL-Poly (lactic acid) is classified as a drug release retardant, which degrades into natural lactic acid monomers, an intermediate product of carbohydrate metabolism, enabling complete drug delivery that lasts for several weeks. Its drug release rate is affected by the pH of the surrounding environment .
Cat. No.: HY-B0396B
CAS No.: 1381788-20-0
Synonyms: L084 hydrobromide
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Tebipenem pivoxil hydrobromide (L084 hydrobromide) is an orally active carbapenem Antibiotic. Tebipenem pivoxil hydrobromide acts as a substrate of OATP1A2 with high affinity for this transporter (Km = 41.1 μM) . Tebipenem pivoxil hydrobromide achieves intestinal absorption via carrier-mediated uptake and simple diffusion. Tebipenem pivoxil hydrobromide inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, multidrug-resistant bacteria, and pathogens producing extended-spectrum β-lactamases. Tebipenem pivoxil hydrobromide eliminates intestinal infection pathogens and reduces mortality in septic mice. Tebipenem pivoxil hydrobromide can be used in research related to bacterial pneumonia, severe gastrointestinal infections, bacterial sepsis, complicated urinary tract infections, and acute pyelonephritis .
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Bathocuproine is a phenanthroline chelator that binds specifically to Cu +. Bathocuproine preferentially binds Cu + over Cu 2+ to form a chromogenic complex, which is used to detect the oxidation state of copper in biomolecules. Bathocuproine undergoes concentration-dependent self-association to form dimers, and it can engage in aromatic stacking interactions with aromatic residues of Aβ (Kd ≈ 1 mM). Bathocuproine is applicable to research related to Alzheimer's disease .
Cat. No.: HY-D3085
CAS No.: 2882924-23-2
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SSR-LDs is a fluorescent probe for lipid droplet polarity detection and lipid droplet imaging. SSR-LDs exhibits polarity-dependent fluorescence: it produces intense short-wavelength emission in low-polarity environments, while generating weak long-wavelength emission in high-polarity environments. SSR-LDs enters cells via free diffusion, specifically targets lipid droplets, and is unaffected by intracellular viscosity or pH values ranging from 4.5 to 9.0. SSR-LDs shows variable Ex/Em wavelengths in different solvents, including 590/663 nm in THF, 600/660 nm in mouse tissue and in vivo imaging, and an excitation wavelength of 580 nm with an emission wavelength range of 610-750 nm in cell imaging. SSR-LDs can be used for research related to fatty liver, liver injury and hepatitis .
Cat. No.: HY-W010514R
CAS No.: 1460-57-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
