130905-04-3
Chemical Structure
Phendioxan
- CAS No.: 130905-04-3
- Formula:C25H27NO5
- Molecular Weight:421.49
IUPAC Name: 2-(2,6-dimethoxyphenoxy)-N-(((2S,3S)-3-phenyl-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)ethan-1-amine
InChIKey: UVEKKXRFQCNLQE-ZEQRLZLVSA-N
SMILES: COC(C=CC=C1OC)=C1OCCNC[C@H]2[C@H](C3=CC=CC=C3)OC4=CC=CC=C4O2
Biological Activity: Phendioxan is a compound with binding activity at the α(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved α(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Phendioxan | Phendioxan is a compound with binding activity at the α(1)-adrenaline receptor subtype. The facilitated membrane diffusion of phendioxan is thought to be associated with improved α(1d)-AR affinity. Docking simulations of phendioxan at biological targets supported the stoichiometric analysis and revealed the importance of polar, electrostatic, hydrophobic, and shape effects of its phenoxy terminal orthogonal substituents on ligand binding. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
