2882924-23-2
Chemical Structure
SSR-LDs
- CAS No.: 2882924-23-2
- Formula:C26H27BF2N2O4
- Molecular Weight:480.31
InChIKey: ABMWEUIIEBLINN-NTEUORMPSA-N
SMILES: CCN(C1=CC=C2C=C(C(OC2=C1)=O)C3=CC(/C=C/C4=CC=C(C=C4)N(C)C)=[O+][B-](F)(O3)F)CC
Biological Activity: SSR-LDs is a fluorescent probe for lipid droplet polarity detection and lipid droplet imaging. SSR-LDs exhibits polarity-dependent fluorescence: it produces intense short-wavelength emission in low-polarity environments, while generating weak long-wavelength emission in high-polarity environments. SSR-LDs enters cells via free diffusion, specifically targets lipid droplets, and is unaffected by intracellular viscosity or pH values ranging from 4.5 to 9.0. SSR-LDs shows variable Ex/Em wavelengths in different solvents, including 590/663 nm in THF, 600/660 nm in mouse tissue and in vivo imaging, and an excitation wavelength of 580 nm with an emission wavelength range of 610-750 nm in cell imaging. SSR-LDs can be used for research related to fatty liver, liver injury and hepatitis[1][2].
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SSR-LDs | SSR-LDs is a fluorescent probe for lipid droplet polarity detection and lipid droplet imaging. SSR-LDs exhibits polarity-dependent fluorescence: it produces intense short-wavelength emission in low-polarity environments, while generating weak long-wavelength emission in high-polarity environments. SSR-LDs enters cells via free diffusion, specifically targets lipid droplets, and is unaffected by intracellular viscosity or pH values ranging from 4.5 to 9.0. SSR-LDs shows variable Ex/Em wavelengths in different solvents, including 590/663 nm in THF, 600/660 nm in mouse tissue and in vivo imaging, and an excitation wavelength of 580 nm with an emission wavelength range of 610-750 nm in cell imaging. SSR-LDs can be used for research related to fatty liver, liver injury and hepatitis. | |||||||||||||||||||||
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References
- [1]. Tang Y, et al. An ultrasensitive lipid droplet-targeted NIR emission fluorescent probe for polarity detection and its application in liver disease diagnosis. Journal of materials chemistry. B. 2022 Sep 21;10(36):6974-6982.
- [2]. He L, et al. Recent advances in fluorescent probes for fatty liver imaging by detecting lipid droplets. Journal of materials chemistry. B. 2024 Oct 17;12(40):10149-10162.
