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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
ACCS
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "ACCS" in MCE Product Catalog:
Cat. No.: HY-P10003A
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Cat. No.: HY-127128
CAS No.: 88844-73-9
Synonyms: ACC-9089 sulfate
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Flestolol (ACC-9089) sulfate is a competitive, ultra-short-acting beta-adrenergic blocking agent. Flestolol sulfate shows a half-life of approximately 6.5 minutes. Flestolol sulfate has the potential for the research of chest pain .
Cat. No.: HY-P10002A
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Cat. No.: HY-N3055
CAS No.: 31685-80-0
Cat. No.: HY-170931
CAS No.: 2252336-04-0
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AMPK activator 16 (compound 6) is a AMP-activated protein kinase (AMPK) inhibitor. AMPK activator 16 shows the most efficient interactions with the key residues of AMPK and demonstrates significant activation of AMPK. AMPK activator 16 increases the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) (p-ACC) and phosphorylated raptor (p-raptor), in N2a cells .
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SABA1 possesses antibacterial properties against Pseudomonas aeruginosa and Escherichia coli, with an IC50 of 4.0 µM against E. coli ACC .
Cat. No.: HY-169010
CAS No.: 2227423-38-1
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Pomalidomide-CO-C5-Br (Compound 6b) is a conjugated compound of the E3 ligand Pomalidomide and linker. It can be used to synthesize highly effective PROTAC molecules targeting ADC (HY-169008) .
Cat. No.: HY-N0853R
CAS No.: 19885-10-0
Cat. No.: HY-N0772R
CAS No.: 24699-16-9
Cat. No.: HY-189391
CAS No.: 3027705-65-0
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PF-07905428 is a topical acetyl-CoA carboxylase (ACC) inhibitor designed to minimize systemic exposure. PF-07905428 inhibits ACC, reduces sebaceous lipid production in the skin. PF-07905428 can be used for the research of acne vulgaris .
Cat. No.: HY-183919
CAS No.: 2237229-78-4
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ACC2-IN-1 is an orally active, selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), with an IC50 of 1.9 nM against human targets. ACC2-IN-1 acts as a reducing agent to decrease malonyl-CoA levels in skeletal muscle and exhibits a favorable CYP450 inhibition profile. ACC2-IN-1 can be used in the research of type 2 diabetes .
Cat. No.: HY-137846A
CAS No.: 2334472-62-5
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PF-05221304 tromethamine is an orally active, liver-directed and dual ACC1/ACC2 inhibitor with IC50s of 7.5 nM for rat ACC1, 8.2 nM for rat ACC2. PF-05221304 tromethamine is a substrate for organic anion transport polypeptides. PF-05221304 tromethamine directly improves a variety of non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH) pathogenic factors .
Cat. No.: HY-107709R
CAS No.: 1039758-22-9
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MK-4074 (Standard) is the analytical standard of MK-4074 (HY-107709). This product is intended for research and analytical applications. MK-4074 is a liver-specific inhibitor of acetyl-CoA carboxylase ACC1 and ACC2 with IC50 values of approximately 3 nM.
Cat. No.: HY-E71732
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[Acetyl-CoA carboxylase]-phosphatase (EC 3.1.3.44) is a phosphomonoesterase that restores the activity of acetyl-CoA carboxylase (ACC) primarily by removing phosphate groups from the enzyme.
Cat. No.: HY-101842R
CAS No.: 1434639-57-2
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ND-646 (Standard) is the analytical standard of ND-646 (HY-101842). This product is intended for research and analytical applications. ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
Cat. No.: HY-187021
CAS No.: 81017-23-4
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3-Carboxyumbelliferyl acetate (compound ACC) is a fluorescent substrate that can be used to detect the activity of the Escherichia coli polysaccharide deacetylase PgaB, with a Km of 1.2 mM. 3-Carboxyumbelliferyl acetate undergoes acetate hydrolysis under the catalysis of E. coli PgaB. 3-Carboxyumbelliferyl acetate can be used in studies related to PgaB enzymatic activity and the mechanism of bacterial biofilm formation .
Cat. No.: HY-102066R
CAS No.: 1079274-94-4
Synonyms: AZD-7451 (Standard)
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Utatrectinib (Standard) is the analytical standard of Utatrectinib (HY-102066). This product is intended for research and analytical applications. Utatrectinib (AZD-7451) is a potent, selective and orally active Trk inhibitor. Utatrectinib blocks TrkC activation and associated tumorigenic behaviors .
Cat. No.: HY-184939
CAS No.: 3063509-17-8
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THR-β agonist 12 is an orally active, potent, and highly selective thyroid hormone receptor β (THR-β) agonist (EC50 = 36 nM). THR-β agonist 12 shows no significant activity against THRα and exhibits no cardiotoxicity in vivo. THR-β agonist 12 inhibits lipid synthesis by activating the AMPK-ACC-SREBP1 signaling axis. THR-β agonist 12 can be used on research into metabolic dysfunction-associated steatohepatitis (MASH) and related metabolic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
