1079274-94-4
1079274-94-4
Chemical Structure
Utatrectinib
Synonym(s): AZD-7451
- CAS No.: 1079274-94-4
- Formula:C18H19FN8O
- Molecular Weight:382.39
IUPAC Name: (S)-N-(1-(5-fluoropyrimidin-2-yl)ethyl)-3-(5-isopropoxy-1H-pyrazol-3-yl)-3H-imidazo[4,5-b]pyridin-5-amine
InChIKey: AYOOGWWGECJQPI-NSHDSACASA-N
SMILES: CC(C)OC1=CC(N2C=NC3=CC=C(N[C@H](C4=NC=C(F)C=N4)C)N=C32)=NN1
Biological Activity: Utatrectinib (AZD-7451) is a potent, selective and orally active Trk inhibitor. Utatrectinib blocks TrkC activation and associated tumorigenic behaviors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Utatrectinib | 98.72% | Utatrectinib (AZD-7451) is a potent, selective and orally active Trk inhibitor. Utatrectinib blocks TrkC activation and associated tumorigenic behaviors. | ||||||||||||||||||||
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Utatrectinib (Standard) | ≥98% | Utatrectinib (Standard) is the analytical standard of Utatrectinib (HY-102066). This product is intended for research and analytical applications. Utatrectinib (AZD-7451) is a potent, selective and orally active Trk inhibitor. Utatrectinib blocks TrkC activation and associated tumorigenic behaviors. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.52
HY-15590AZ-23 -
Similarity Score 0.49
HY-10193AR(1R)-AZD-1480 (Standard) -
Similarity Score 0.49
HY-10193RAZD-1480 (Standard) -
Similarity Score 0.47
HY-164461AZD6918 -
Similarity Score 0.46
HY-175302TRK-IN-32 -
Similarity Score 0.45
HY-181780TRK-IN-34 -
Similarity Score 0.45
HY-153224GLPG2534 -
Similarity Score 0.45
HY-118374AM-9635 -
Similarity Score 0.44
HY-120116AM-8508 -
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