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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
87 Results for "
ACCS
" in MedChemExpress (MCE) Product Catalog:
Products (87)
87 Results for "ACCS" in MCE Product Catalog:
Cat. No.: HY-P10003B
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Cat. No.: HY-16943
CAS No.: 155233-31-1
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Cat. No.: HY-150191
CAS No.: 2315406-63-2
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IMA-1 is an inhibitor that inhibits the interaction between arachidonic acid 12-lipoxygenase (ALOX12) and acetyl-CoA carboxylase 1 (ACC1). IMA-1 significantly blocks the progression of diet-induced non-alcoholic steatohepatitis (NASH) in male mice and crab-eating monkeys, and does not cause hyperlipidemia. IMA-1 can be used for the study of NASH .
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2,5-Anhydro-D-glucitol-1,6-diphosphate is a competitive PFK-1 inhibitor. 2,5-Anhydro-D-glucitol-1,6-diphosphate inhibits the enzymatic activity of PFKP without altering the non-glycolytic regulatory function of PFKP. 2,5-Anhydro-D-glucitol-1,6-diphosphate does not change mitochondrial AMPK levels, ACC2 phosphorylation levels, long-chain free fatty acid levels, or ROS levels under glucose starvation conditions. 2,5-Anhydro-D-glucitol-1,6-diphosphate is used in related research on non-small cell lung cancer .
Cat. No.: HY-173565
CAS No.: 2270839-89-7
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ACC-IN-1 (Compound B1) is an allosteric inhibitor of acetyl-CoA carboxylase (ACC). ACC-IN-1 targets ACC to regulate lipid metabolism, which can improve liver steatosis, inflammation related to non-alcoholic steatohepatitis (NASH) .
Cat. No.: HY-16946
CAS No.: 591778-83-5
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CP-610431 is a reversible, ATP-uncompetitive, isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor. CP-610431 inhibits ACC1 and ACC2 with IC50s of ~50 nM. CP-610431 can be used for the research of metabolic syndrome .
Cat. No.: HY-121273
CAS No.: 40843-25-2
Synonyms: Dichlorfop acid; (±)-Diclofop
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Diclofop (Dichlorfop acid) is an acetyl-CoA carboxylase (ACC) inhibitor. Diclofop is also the major metabolite of the herbicide Diclofop-methyl (HY-136367). Diclofop exhibits antimalarial activity with an IC50 of 210 μM against P. falciparum .
Cat. No.: HY-169009
CAS No.: 382608-09-5
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(Rac)-Spirotetramat-enol is a ligand of acetyl-CoA carboxylase (ACC) that can be used for the synthesis of PROTAC ACC degrader-1 (HY-169008). (Rac)-Spirotetramat-enol binds to the carboxyltransferase domain and inhibits ACC activity in insects and spider mites. (Rac)-Spirotetramat-enol exhibits insecticidal activity against nymphs of the black bean aphid. (Rac)-Spirotetramat-enol can be used in studies related to black bean aphid infestation .
Cat. No.: HY-147930
CAS No.: 2350219-22-4
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ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research .
Cat. No.: HY-42632
CAS No.: 2131091-32-0
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ACC1/2-IN-3 (example 66) is an ACC1 and ACC2 inhibitor with an IC50 value of 1-10 nM for both. ACC1/2-IN-3 can be used for the study of diseases mediated by ACC, such as metabolic disease .
Cat. No.: HY-N7521
CAS No.: 37064-31-6
Synonyms: Procyanidine C2
Cat. No.: HY-16901R
CAS No.: 1434635-54-7
Synonyms: ND-630 (Standard); GS-0976 (Standard); NDI-010976 (Standard)
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Firsocostat (Standard) is the analytical standard of Firsocostat. This product is intended for research and analytical applications. Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.
Cat. No.: HY-P99527
CAS No.: 886584-10-7
Synonyms: ACC-001; PF 05236806
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Cat. No.: HY-16901A
CAS No.: 2128714-16-7
Synonyms: ND-630 (S enantiomer); GS-0976 (S enantiomer); NDI-010976 (S enantiomer)
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Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase (ACC) inhibitor.
Cat. No.: HY-RS00146
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ACCS Human Pre-designed siRNA Set A contains three designed siRNAs for ACCS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-161976
CAS No.: 3027705-67-2
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ACC1-IN-2 (Compound 16) is an ACC1 inhibitor with an IC50 of 7.3 nM. ACC1-IN-2 can be used in the study of acne .
Cat. No.: HY-169008
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PROTAC ACC degrader-1 is an Acetyl-CoA Carboxylase PROTAC degrader with insecticidal activity, which induces ACC protein degradation via the ubiquitin-proteasome system. PROTAC ACC degrader-1 exhibits significant dose-dependent insecticidal activity against Aphis craccivora nymphs. PROTAC ACC degrader-1 can be used in studies related to Aphis craccivora infestation .
Cat. No.: HY-19000
CAS No.: 90446-66-5
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ACC-9358 is an orally active sodium channel blocker. ACC-9358 has antiarrhythmic activity. ACC-9358 can be used in research on cardiovascular diseases such as arrhythmias .
Cat. No.: HY-N16232
CAS No.: 3091880-01-9
Synonyms: 2-α-Carboxy cholestanol
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2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC50 of ～5 μM.
Cat. No.: HY-P10003
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
