2237229-78-4
2237229-78-4
Chemical Structure
ACC2-IN-1
- CAS No.: 2237229-78-4
- Formula:C20H20ClN3O3S
- Molecular Weight:417.91
InChIKey: CYSWUSAYJNCAKA-FYJFLYSWSA-N
SMILES: ClC1=C2C(N=C(S2)OCC)=CC=C1OC3=CC=C(C=N3)/C=C/[C@H](C)NC(C)=O
Biological Activity: ACC2-IN-1 is an orally active, selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), with an IC50 of 1.9 nM against human targets. ACC2-IN-1 acts as a reducing agent to decrease malonyl-CoA levels in skeletal muscle and exhibits a favorable CYP450 inhibition profile. ACC2-IN-1 can be used in the research of type 2 diabetes[1].
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ACC2-IN-1 | ACC2-IN-1 is an orally active, selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), with an IC50 of 1.9 nM against human targets. ACC2-IN-1 acts as a reducing agent to decrease malonyl-CoA levels in skeletal muscle and exhibits a favorable CYP450 inhibition profile. ACC2-IN-1 can be used in the research of type 2 diabetes. | |||||||||||||||||||||
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References
Keywords
