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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
biliary
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "biliary" in MCE Product Catalog:
Cat. No.: HY-P75358
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM1; CD66a; Prev. BGP; biliary Glycoprotein 1; BGP1; CEACAM1 Protein; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (biliary Glycoprotein); Antigen CD66; Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; BGP-1; Cell Adhesion Molec
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77630
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CEACAM1; CD66a; Prev. BGP; biliary Glycoprotein 1; BGP1; CEACAM1 Protein; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (biliary Glycoprotein); Antigen CD66; Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; BGP-1; Cell Adhesion Molec
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75360
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM1; CD66a; Prev. BGP; biliary Glycoprotein 1; BGP1; CEACAM1 Protein; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (biliary Glycoprotein); Antigen CD66; Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; BGP-1; Cell Adhesion Molec
Species:
Mouse
Source:
HEK293
Cat. No.: HY-N9516AR
CAS No.: 57011-24-2
Research Areas:
Taurodehydrocholic acid (sodium) (Standard) is the analytical standard of Taurodehydrocholic acid (sodium) (HY-N9516A). This product is intended for research and analytical applications. Taurodehydrocholic acid sodium is a biliary cholesterol secretion activator. Taurodehydrocholic acid sodium significantly increases the expression of Abcg5 and decreases the expression of abc8. Taurodehydrocholic acid sodium can be used in the study of cholesterol metabolism .
Cat. No.: HY-P78894
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM1; CD66a; Prev. BGP; biliary Glycoprotein 1; BGP1; CEACAM1 Protein; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (biliary Glycoprotein); Antigen CD66; Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; BGP-1; Cell Adhesion Molec
Species:
Human
Source:
HEK293
Cat. No.: HY-N0545S2
Synonyms: Sodium taurocholate-d4-1 ; N-Choloyltaurine-d4-1 sodium
Target:
Research Areas:
Saccharolactone is a potent orally active β-glucuronidase inhibitor. Saccharolactone markedly lowers biliary endogenous β-glucuronidase activity in the rat bile. Saccharolactone can stabilize glucuronide metabolites in vitro. Saccharolactone is also a strong inhibitor of CYP1A2, 2D6, 3A4 and 2C8 isoforms (IC50 < 4 mM) .
Cat. No.: HY-116755S2
Synonyms: CR 605-d5 oxalate
Cat. No.: HY-P85448
Synonyms: DLAT; DLTA; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; mitochondrial; 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; PBC; Dihydrolipoamide acetyltransferase component of pyruva
Cat. No.: HY-175400
CAS No.: 3110535-99-1
Synonyms: 6-PPD-quinone-4-OH
Research Areas:
6-PPD-Q-4-OH (6-PPD-quinone-4-OH) is a metabolite of 6PPD-Q (HY-153169). 6-PPD-Q-4-OH is applicable to exposure studies of 6PPD-Q, an environmental pollutant .
Cat. No.: HY-180131
CAS No.: 1312993-34-2
Synonyms: ASB17061
Target:
Research Areas:
INVA8001 (ASB17061) is a highly selective and orally active chymase inhibitor with IC50 values for human chymase and mouse mast cell proteinase 4 (mMCP-4) of 0.02 and 0.03 μM, respectively. INVA8001 exhibits IC50 values for bovine α-chymotrypsin and human cathesin G of 3.4 and 32.1 μM, respectively, and it shows over 1000-fold selectivity for other related serine proteases. INVA8001 inhibits mast cells in a mouse primary sclerosing cholangitis (PSC) model, improves bile duct pathology, and alleviates bile stasis, demonstrating anti-inflammatory and anti-fibrotic effects .
Cat. No.: HY-P80292
Synonyms: DLTA, DLAT, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, M2 antigen complex 70 kDa subunit, Pyruvate dehydrogenase complex component E2, PBC, PDC-E2, PDCE2
Cat. No.: HY-189393
CAS No.: 3089177-97-6
Target:
Research Areas:
RTY-406 is an orally active ABCB4/MDR3 and ABCB11/BSEP positive modulator. RTY-406 increases ABCB4/MDR3 and ABCB11/BSEP protein levels and functional output, elevates biliary phospholipid levels, enhances bile acid efflux, increases bile flow and micelle formation, reduces hepatic bile acids, and promotes cholesterol-to-bile-acid conversion. RTY-406 does not induce hepatocellular injury, maintains normal serum alanine transaminase and aspartate aminotransferase levels, and shows a favorable safety profile in cynomolgus monkeys. RTY-406 can be used for the research of primary sclerosing cholangitis and cholestasis .
Cat. No.: HY-P992454
Cat. No.: HY-P1654A
CAS No.: 3107375-56-1
Cat. No.: HY-183947
CAS No.: 56943-06-7
Target:
Research Areas:
4-Bromolevamisole, an analogues of Levamisole (HY-A0106), is a phosphatase inhibitor. 4-Bromolevamisole potentiates the antineoplastic activity of 5-Fluorouracil (HY-90006), its analogues, or prodrugs thereof.4-Bromolevamisole can be used for cancer research .
Cat. No.: HY-184371
CAS No.: 2907719-42-8
Target:
Research Areas:
MC-GGFG-Eribulin is a linker-payload of a tubulin inhibitor-based cytotoxic agent with an N-substituted maleimide group, conjugated via the MC-GGFG linker. MC-GGFG-Eribulin reacts with the thiol groups of reduced antibodies or antigen-binding fragments to form antibody-drug conjugates. MC-GGFG-Eribulin is applicable for cancer-related research .
Cat. No.: HY-182537
CAS No.: 119302-18-0
Target:
Research Areas:
Org 9616 bromide is a non-depolarizing neuromuscular blocker with a structure similar to Pancuroniam. Org 9616 bromide induces rapid-onset, short-duration neuromuscular blockade .
Cat. No.: HY-P85556
Synonyms: 70 kDa mitochondrial autoantigen of primary biliary cirrhosis; anti DLAT; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Dihydrolipoamide; Dihydrolipoamide S Acetyltransferase; Dihydrolipoamide S-acetyltransferase; E2 component of pyruvate dehydrogenase complex; Dihydrolipoamide S-Acetyltransferase; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial; DLAT; DLAT; DLTA; E2; E2 component of pyruvate dehydrogenase complex; M2 antigen complex 70 kDa subunit; M2 Antigen Complex 70kD Subunit; mitochondrial; ODP2_HUMAN; PBC; PDC E2; PDC-E2; PDCE2; Pyruvate dehydrogenase complex component E2; Pyruvate dehydrogenase complex E2 subunit; S acetyltransferase component of pyruvate dehydrogenase complex.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
