Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
PDGF
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "PDGF" in MCE Product Catalog:
Cat. No.: HY-P78194
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: PDGFRB; PDGFR-Beta; Prev. PDGFR; Beta Platelet-Derived Growth Factor Receptor; PDGFR1; Activated Tyrosine Kinase PDGFRB; CD140b; CD140b Antigen; JTK12; NDEL1-PDGFRB; Platelet-Derived Growth Factor Receptor, Beta Polypeptide; IBGC4; Beta-Type Platelet-Deri
Species:
Human
Source:
HEK293
Cat. No.: HY-P80510
Synonyms: CD140a, PDGFR2, RHEPDGFRA, PDGFRA, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGFR-2
Cat. No.: HY-P86319
Synonyms: Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; PDGFR-2; CD antigen CD140a;
Cat. No.: HY-P705568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PDGFRA; CD140a Antigen; Platelet Derived Growth Factor Receptor Alpha; PDGF-R-Alpha; PDGFR2; PDGFR-2; Platelet-Derived Growth Factor Receptor Alpha; GAS9; CD140a; Platelet-Derived Growth Factor Receptor-Like Protein; Platelet-Derived Growth Factor Receptor, Alpha Polypeptide; Platelet-Derived Growth Factor Alpha Receptor; Alpha-Type Platelet-Derived Growth Factor Receptor; Alpha Platelet-Derived Growth Factor Receptor; Platelet-Derived Growth Factor Receptor 2; PDGFR-Alpha; CD140 Antigen-Like Family Member A; RHEPDGFRA
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702756
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PDGFRB; PDGFR-Beta; Prev. PDGFR; Beta Platelet-Derived Growth Factor Receptor; PDGFR1; Activated Tyrosine Kinase PDGFRB; CD140b; CD140b Antigen; JTK12; NDEL1-PDGFRB; Platelet-Derived Growth Factor Receptor, Beta Polypeptide; IBGC4; Beta-Type Platelet-Derived Growth Factor Receptor; OPDKD; Platelet-Derived Growth Factor Receptor Beta; PENTT; Platelet-Derived Growth Factor Receptor 1; IMF1; CD140 Antigen-Like Family Member B; KOGS; PDGF-R-Beta; Platelet Derived Growth Factor Receptor Beta; PDGFR-1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706082
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PDGFRA; CD140a Antigen; Platelet Derived Growth Factor Receptor Alpha; PDGF-R-Alpha; PDGFR2; PDGFR-2; Platelet-Derived Growth Factor Receptor Alpha; GAS9; CD140a; Platelet-Derived Growth Factor Receptor-Like Protein; Platelet-Derived Growth Factor Receptor, Alpha Polypeptide; Platelet-Derived Growth Factor Alpha Receptor; Alpha-Type Platelet-Derived Growth Factor Receptor; Alpha Platelet-Derived Growth Factor Receptor; Platelet-Derived Growth Factor Receptor 2; PDGFR-Alpha; CD140 Antigen-Like Family Member A; RHEPDGFRA
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-174507
Human VEGFD mRNA encodes the human vascular endothelial growth factor D (VEGFD) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is structurally and functionally similar to vascular endothelial growth factor C (VEGFC).
Cat. No.: HY-10527CR
CAS No.: 332013-26-0
Synonyms: Bay 57-9352 mesylate (Standard)
Target:
Research Areas:
Telatinib (mesylate) (Standard) is the analytical standard of Telatinib (mesylate). This product is intended for research and analytical applications. Telatinib mesylate (Bay 57-9352 mesylate) is a potent and orally active VEGFR2, VEGFR3, PDGFα, and c-Kit inhibitor with IC50s of 6 nM, 4 nM, 15 nM and 1 nM, respectively .
Cat. No.: HY-10527R
CAS No.: 332012-40-5
Synonyms: Bay 57-9352 (Standard)
Target:
Research Areas:
Telatinib (Standard) is the analytical standard of Telatinib. This product is intended for research and analytical applications. Telatinib (Bay 57-9352) is an orally active, small molecule inhibitor of VEGFR2, VEGFR3, PDGFα, and c-Kit with IC50s of 6, 4, 15 and 1 nM, respectively.
Target:
Cat. No.: HY-174508
Human VEGFC mRNA encodes the human vascular endothelial growth factor C (VEGFC) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFC promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels.
Cat. No.: HY-138813A
CAS No.: 1261432-05-6
Synonyms: (E/Z)-SU-12662 hydrochloride
Target:
Research Areas:
(E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP .
Cat. No.: HY-E70803
PDGF-BB/PDGFRβ signaling plays an important role during vascularization by mediating pericyte recruitment to the vasculature, promoting the integrity and function of vessels. Biotin-PDGFRβ Recombinant Human Active Protein Kinase is a recombinant PDGFRβ protein that can be used to study PDGFRβ-related functions, and is biotinylated .
Research Areas:
Bucladesine (Dibutyryl cAMP; DBcAMP) is a membrane-permeable 3′, 5′-cyclic adenosine monophosphate (cAMP) analog. Bucladesine selectively activates cAMP dependent protein kinase (PKA) by increasing the intracellular level of cAMP. Bucladesine significantly attenuates MDMA-induced increases in hippocampal mitochondrial ROS formation, mitochondrial outer membrane damage, cytochrome c release, and hippocampal ADP/ATP ratio, thereby improving spatial learning and memory impairments. Bucladesine exhibit anti-nociceptive and anti-inflammation effect. Bucladesine can inhibit cancer cells proliferation, induce apoptosis. Bucladesine can be used for the researches of neurological disease, cancer, inflammation .
Cat. No.: HY-148316
CAS No.: 186610-88-8
hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents .
Cat. No.: HY-16018
CAS No.: 1227939-82-3
Synonyms: ABT-348
Target:
Research Areas:
Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib also is a potent VEGF, PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) .
Cat. No.: HY-16018A
CAS No.: 1847485-91-9
Synonyms: ABT-348 hydrochloride
Target:
Research Areas:
Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) .
Cat. No.: HY-103032R
CAS No.: 778274-97-8
Target:
Research Areas:
Multi-kinase inhibitor 1 (Standard) is the analytical standard of Multi-kinase inhibitor 1 (HY-103032). This product is intended for research and analytical applications. Multi-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl .
Category:
Oleaceae Fraxinus rhynchophylla Hance Coumarins Phenols Polyphenols Phenylpropanoids Plants
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
