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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
139 Results for "
Quorum sensing
" in MedChemExpress (MCE) Product Catalog:
Products (139)
139 Results for "Quorum sensing" in MCE Product Catalog:
Cat. No.: HY-W035904R
CAS No.: 539-80-0
Synonyms: Cycloheptatrienone (Standard)
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Cat. No.: HY-E71703
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3-Hydroxy-5-phosphonooxypentane-2,4-dione thiolase (EC 2.3.1.245) participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
Cat. No.: HY-E71072
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(4S)-4-Hydroxy-5-phosphonooxypentane-2,3-dione isomerase (EC 5.3.1.32) participates in a degradation pathway of the bacterial quorum-sensing autoinducer molecule AI-2.
Cat. No.: HY-W788542
CAS No.: 205514-29-0
Quoromycin is an orally active SmcR inhibitor with a Kd of 0.697 μM for Vibrio vulnificus SmcR. Quoromycin binds directly to SmcR, reduces its DNA-binding affinity, and inhibits the quorum sensing signaling pathway. Quoromycin is applicable to the research of Vibrio vulnificus infection .
Cat. No.: HY-W904855
CAS No.: 177562-78-6
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Apicidin D2 (Compound 4), a fungal metabolite, is a Accessory gene regulator A (AgrA) quorum-sensing inhibitor. Apicidin D2 has anti-virulence activity. Apicidin D2 suppresses MRSA agr activation and shows potent inhibitory activities against all agr types in a nonbiocidal manner. Apicidin D2 can be used for MRSA infections research .
Cat. No.: HY-N10572
CAS No.: 2831355-88-3
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QStatin is a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with an EC50 of 208.9 nM, binding tightly to SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin shows pan-QS (Vibrio quorum sensing) inhibitor activity in diverse Vibrio species and attenuates their virulence in an aquatic host. QStatin may be a sustainable antivibriosis agent useful in aquacultures .
Cat. No.: HY-N3043A
CAS No.: 56973-65-0
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Cat. No.: HY-Y0248AS
CAS No.: 166447-71-8
Synonyms: trans,trans-Farnesol-d6; (2E,6E)-Farnesol-d6
Synonyms: trans,trans-Farnesol (Standard); (2E,6E)-Farnesol (Standard)
Cat. No.: HY-W008270R
CAS No.: 497-23-4
Synonyms: γ-Crotonolactone (Standard)
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2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density .
Cat. No.: HY-N12165
CAS No.: 213547-11-6
Category:
Flavonoids Microorganisms Xanthones Phenols Other Flavonoids
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Cat. No.: HY-W127487
CAS No.: 479050-96-9
Cat. No.: HY-189260
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FNT12 is a synthetic heterocyclic derivative of 1,2,4-triazolo[1,5-a]pyrimidine that exhibits narrow-spectrum antibacterial activity against Pseudomonas aeruginosa. FNT12 possesses antibiofilm activity and free radical-scavenging antioxidant activity. FNT12 is predicted to bind to the Pseudomonas aeruginosa quorum-sensing protein LasR. FNT12 can be used in research on Pseudomonas aeruginosa infection .
Cat. No.: HY-N8261
CAS No.: 77674-99-8
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Cat. No.: HY-W010608R
CAS No.: 3188-00-9
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Cat. No.: HY-175254
Antibiofilm agent-17 is a dual-action biofilm inhibitor against Pseudomonas aeruginosa (IC50 = 0.33 μM). Antibiofilm agent-17 inhibits biofilm growth by reducing quorum sensing-mediated virulence production and iron ion acquisition. Antibiofilm agent-17 exhibits synergistic antimicrobial effects in a mouse wound infection model. Antibiofilm agent-17 can be used in research on combating Pseudomonas aeruginosa infections .
Cat. No.: HY-W008806S
Synonyms: OHHL-d3; N-(3-Oxohexanoyl)homoserine lactone-d3
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N-(3-Oxohexanoyl)-L-homoserine lactone-d3 (OHHL-d3) is the deuterated-labeled N-(3-Oxohexanoyl)-L-homoserine lactone (HY-W008806). N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL; N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 μM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
