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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
platelet-activating factor
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "platelet-activating factor" in MCE Product Catalog:
Cat. No.: HY-108634R
CAS No.: 105219-56-5
Synonyms: WEB 2086 (Standard)
Research Areas:
Apafant (Standard) is the analytical standard of Apafant (HY-108634). This product is intended for research and analytical applications. Apafant (WEB 2086), a chemical probe, is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
Cat. No.: HY-P77444
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (platelet-activating factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (platelet-activating factor Acetylhydrolase, Plas
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P700568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (platelet-activating factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Synonyms: MKS 492
Target:
Research Areas:
SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats .
Cat. No.: HY-118915
CAS No.: 50655-20-4
Synonyms: A26771E
Category:
Target:
Cat. No.: HY-N12707
CAS No.: 145722-88-9
Cat. No.: HY-124887
CAS No.: 99046-40-9
Research Areas:
L 651142 is a weak platelet activating factor (PAF) receptor antagonist. L 651142 inhibits the binding of [ 3H]PAF to rabbit platelet, human platelet or human lung membranes with Kis of 0.839 μM, 1.82 μM, 3.64 μM, respectively .
Cat. No.: HY-126551
CAS No.: 474944-25-7
Research Areas:
Butenoyl-PAF is a phospholipid analog of platelet activating factor (PAF-like) that is generated in oxidized low-density lipoprotein (DLDR). Butenoyl-PAF can activate cells that express human PAF receptors, such as neutrophils, monocytes, and platelets, and it stimulates an increase in intracellular calcium ion concentration .
Cat. No.: HY-N10754
CAS No.: 13060-15-6
Target:
Research Areas:
CV-6209 is a potent antagonist of platelet activating factor (PAF). CV-6209 inhibits the PAF-induced aggregation of rabbit and human platelets, with IC50s of 75 nM and 170 nM, respectively. CV-6209 can inhibit PAF-induced hypotension in rats .
Cat. No.: HY-N14932
CAS No.: 19207-26-2
Category:
Cat. No.: HY-N14933
CAS No.: 104700-85-8
Category:
Cat. No.: HY-N14934
CAS No.: 104700-86-9
Category:
Cat. No.: HY-108908R
CAS No.: 122956-68-7
Synonyms: UK-74505 (Standard)
Research Areas:
(Rac)-Modipafant (Standard) is the analytical standard of (Rac)-Modipafant (HY-108908). This product is intended for research and analytical applications. (Rac)-Modipafant (UK-74505) is an orally active, selective, long-acting irreversible platelet activating factor receptor (PAFR) antagonist. (Rac)-Modipafant prevents dengue infection .
Cat. No.: HY-102004R
CAS No.: 412950-08-4
Synonyms: SB 659032 (Standard)
Target:
Research Areas:
Rilapladib (Standard) is the analytical standard of Rilapladib (HY-102004). This product is intended for research and analytical applications. Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM . Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist .
Cat. No.: HY-182418
CAS No.: 138060-13-6
Research Areas:
UR-11353 is a selective platelet activating factor (PAF) antagonist with long-lasting activity. UR-11353 inhibits PAF-induced platelet aggregation in rabbit platelet-rich plasma. UR-11353 inhibits PAF-induced hypotension in normotensive rats. UR-11353 protects against PAF-induced mortality in mice .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
