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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
LP
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "LP" in MCE Product Catalog:
Cat. No.: HY-10521R
CAS No.: 356057-34-6
Synonyms: SB-480848 (Standard)
Research Areas:
Darapladib (Standard) is the analytical standard of Darapladib. This product is intended for research and analytical applications. Darapladib (SB-480848) is an orally active, selective and reversible Lp-PLA2 inhibitor (IC50=0.25 nM). Darapladib can trigger irreversible actions on glioma cell apoptosis and induce cycle arrest. Darapladib can be used in the study of atherosclerosis and cancer .
Research Areas:
MC-Val-Cit-PAB-PROTAC ERα Degrader-1 (compound LP2) consists an ADC linker and a PROTAC, whcih can be conjugated to an antibody to form PACs. MC-Val-Cit-PAB-PROTAC ERα Degrader-1 conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab) .
Cat. No.: HY-P701459
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STAMBPL1; Associated Molecule With The SH3 Domain Of STAM (AMSH) - Family Protein; STAM Binding Protein Like 1; Associated Molecule With The SH3 Domain Of STAM (AMSH) Like Protein; AMSH-LP; AMSH-Like Protease; BA399O19.2; FLJ31524; KIAA1373; STAM Binding
Species:
Human
Source:
E. coli
Cat. No.: HY-P701477
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STAMBPL1; Associated Molecule With The SH3 Domain Of STAM (AMSH) - Family Protein; STAM Binding Protein Like 1; Associated Molecule With The SH3 Domain Of STAM (AMSH) Like Protein; AMSH-LP; AMSH-Like Protease; BA399O19.2; FLJ31524; KIAA1373; STAM Binding
Species:
Human
Source:
E. coli
Cat. No.: HY-P76376
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPR37; Endothelin B Receptor-Like Protein 1; G Protein-Coupled Receptor 37; Prosaposin Receptor GPR37; PAELR; ETBR-LP-1; HET(B)R-LP; Probable G-Protein Coupled Receptor 37; EDNRBL; Endothelin Receptor Type B-Like; G Protein-Coupled Receptor 37 (Endothelin
Species:
Human
Source:
HEK293
Cat. No.: HY-173625
CAS No.: 2928571-52-0
Research Areas:
P5(PEG12)-VC-PAB-Exatecan (LP3) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker P5(PEG24)-VC-PAB to make antibody agent conjugate (ADC). P5(PEG12)-VC-PAB-Exatecan can be used for the research of tumor .
Cat. No.: HY-175183
Antituberculosis agent-15 (Compound 18c) is a selective antimycobacterial agent with MICs of 0.45 and 0.28 μM for M. tuberculosis H37Rv (ATCC 27294) and its wild-type H37Rv-LP (ATCC 25618), respectively. Antituberculosis agent-15 has potent intracellular inhibitory activities in macrophage infection models with IC50s of 0.16 μM. Antituberculosis agent-15 can be used for tuberculosis research .
Target:
Research Areas:
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin (HY-16560) derivative, is a linker-payload of protein-agent conjugates . Dxd (HY-13631D) can be used as a payload for the antibody-coupling drug ADC (DS-8201a).DIBAC-GGFG-NH2CH2-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
Cat. No.: HY-P83206A
Synonyms: GPR37; Probable G-protein coupled receptor 37; Endothelin B receptor-like protein 1; ETBR-LP-1; Parkin-associated endothelin receptor-like receptor; PAELR
Cat. No.: HY-120105
CAS No.: 170747-33-8
Research Areas:
NSC666715 is a DNA polymerase β (Pol-β) inhibitor. NSC666715 directly and specifically interacts with Pol-β, interferes with its binding to damaged DNA, blocks its dRP lyase activity, and inhibits Pol-β-mediated SN- and LP-BER. NSC666715 induces AP site accumulation and S-phase cell cycle arrest, and triggers senescence and apoptosis (apoptosis) via the p53/p21 pathway in colorectal cancer cells. NSC666715 enhances TMZ (HY-17364)-induced DNA damage, senescence and apoptosis, and potentiates the cytotoxicity of TMZ. NSC666715 inhibits tumor growth in colon cancer xenograft models. NSC666715 can be used in research related to colorectal cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
