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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
205 Results for "
Modifier
" in MedChemExpress (MCE) Product Catalog:
Products (205)
205 Results for "Modifier" in MCE Product Catalog:
Cat. No.: HY-P1218A
Target:
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Cat. No.: HY-P81662
Synonyms: GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase Modifier subunit
Cat. No.: HY-P86557
Synonyms: GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase Modifier subunit
Cat. No.: HY-W015114R
CAS No.: 63512-50-5
Synonyms: (S)-2-Hydroxyglutaric acid disodium (Standard)
Cat. No.: HY-W243303J
CAS No.: 9003-01-4
Cat. No.: HY-P85493
Synonyms: CBX 3; CBX3; CBX3_HUMAN; Chromobox homolog 3; HP1 gamma homolog, Drosophila; Chromobox homolog 3; Chromobox protein homolog 3; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; HP1 gamma; HP1 gamma homolog; HP1Hs gamma; Modifier 2 protein.
Cat. No.: HY-L039
3,231 compounds
Techniques for reprogramming somatic cells create new opportunities for drug screening, disease modeling, artificial organ development, and cell therapy. The development of reprogramming techniques has grown exponentially since Yamanaka reprogrammed somatic cells to become induced pluripotent stem cells (iPSCs) using four transcription factors, OCT4, SOX2, KLF4, and c-MYC in 2006. Despite the development of efficient reprogramming methods, most methods are inappropriate for clinical applications because they carry the risk of integrating exogenous genetic factors or use oncogenes. Alternative approaches, such as those based on miRNA, non-viral genes, non-integrative vectors, and small molecules, have been studied as possible solutions to the problems. Among these alternatives, small molecules are attractive options for clinical applications. Reprogramming using small molecules is inexpensive and easy to control in a concentration- and time-dependent manner. It offers a high level of cell permeability, ease of synthesis and standardization, and it is appropriate for mass-producing cells.
MCE Reprogramming Compound Library contains a unique collection of 3,231 compounds that act on reprogramming signaling pathways. These compounds are potential stimulators for reprogramming. This library is a useful tool for researching reprogramming and regenerative medicine.
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KSC-34, a covalent modifier of protein disulfide isomerase A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC50 of 3.5 μM. KSC-34 displays a 30-fold selectivity for a domain over a′ domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family . KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W1061747
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endo-BCN-PEG3 Phosphoramidite is a nucleic acid phosphoramidite modifier containing an endo-bicyclononyne (BCN) group and a PEG3 spacer, enabling site-specific incorporation of endo-BCN-PEG3 into DNA or RNA during solid-phase oligonucleotide synthesis. endo-BCN-PEG3 Phosphoramidite introduces a BCN group that can undergo copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) with azide-containing molecules or inverse electron demand Diels-Alder (IEDDA) reactions with tetrazines, enabling post-synthetic oligonucleotide labeling and bioconjugation.
Cat. No.: HY-W127770
CAS No.: 569-61-9
Synonyms: Basic red 9
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Pararosaniline hydrochloride (Basic red 9) is a pH-responsive basic dye, as a biological stain to track certain proteins. The pH of the acidified Pararosaniline hydrochloride reagent has a significant effect on the color and the maximum absorption wavelength (λmax) of the reaction system, with its optimum pH 0.48 and a λmax at 549 nm. Pararosaniline hydrochloride is also a strong modifier of RNA splicing. Pararosaniline hydrochloride has been used in the analysis of SO2 and formaldehyde and staining of bacteria or other organisms. Pararosaniline hydrochloride is extensively used in industries like textile, printing, paper, cosmetic, and leather .
Cat. No.: HY-W020780
CAS No.: 724722-89-8
Synonyms: mPEG5000-Maleimide
Cat. No.: HY-P70974
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SUMO2; SMT3 (Suppressor Of Mif Two 3, Yeast) Homolog 2; Prev. SMT3H2; SMT3 Suppressor Of Mif Two 3 Homolog 2; SMT3B; Sentrin 2; Small Ubiquitin-Related Modifier 2; Sentrin-2; Ubiquitin-Like Protein SMT3B; SUMO-3; SMT3 Homolog 2; SUMO-2; HSMT3; Smt3B; SMT3
Species:
Human
Source:
E. coli
Cat. No.: HY-P1218B
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Cat. No.: HY-W133907
CAS No.: 55566-30-8
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Tetrakis (hydroxymethyl) phosphonium sulfate is a protein crosslinker and hydrogel modifier. Tetrakis (hydroxymethyl) phosphonium sulfate covalently binds to primary and secondary amines of amino acids or proteins via a Mannich-type reaction, thereby constructing stable crosslinking bonds between protein molecules. Tetrakis (hydroxymethyl) phosphonium sulfate not only regulates the gelation time and storage modulus of recombinant elastin-like protein hydrogels, but also exhibits excellent cytocompatibility, and supports the differentiation and growth of embryonic stem cells and neural cells in a three-dimensional encapsulation environment. Tetrakis (hydroxymethyl) phosphonium sulfate is suitable for protein-based hydrogel systems, especially for applications related to cell encapsulation .
Cat. No.: HY-W744986
Synonyms: (2S)-2-Hydroxyglutaric acid-d5 disodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
