![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan](https://file.medchemexpress.com/product_pic/hy-173634.gif "Click to View Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan Product Detail")
![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB](https://file.medchemexpress.com/product_pic/hy-173635.gif "Click to View Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
118 Results for "
(3S,3'S)-astaxanthin
" in MedChemExpress (MCE) Product Catalog:
Products (118)
118 Results for "(3S,3'S)-astaxanthin" in MCE Product Catalog:
573
573 Publications Verification
Synonyms: (1S,3R)-RSL3
Research Areas:
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
34
34 Cited Publications
Research Areas:
iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 (HY-100218A) .
3
3 Cited Publications
Target:
Research Areas:
(1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
2
2 Cited Publications
Cat. No.: HY-W050031
CAS No.: 6168-83-8
Synonyms: (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid
Category:
Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-W747072
CAS No.: 71781-33-4
Synonyms: 3-Sulfocholyl Taurine; TCA3S
Target:
Research Areas:
3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine; TCA3S) is a metabolite of the conjugated bile acid taurocholic acid. Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.
Cat. No.: HY-173634
CAS No.: 3059991-66-8
Research Areas:
Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan (LP1) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB (HY-173635) to make antibody agent conjugate (ADC), AZD0516 (HY-173639) .
Cat. No.: HY-W009110
CAS No.: 261165-06-4
Target:
Research Areas:
Cat. No.: HY-79691
CAS No.: 122536-76-9
Cat. No.: HY-W076441
CAS No.: 56816-01-4
Synonyms: Ethyl (S)-3-hydroxybutyrate
Cat. No.: HY-W004812
CAS No.: 161660-94-2
Synonyms: (1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
Target:
Research Areas:
BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research .
Cat. No.: HY-N2380
CAS No.: 132201-33-3
Category:
Alkaloids Other Alkaloids Taxaceae Plants Disease Research Fields Cancer Taxus wallichiana Zucc.
Target:
Synonyms: 3HPG
Target:
Research Areas:
(Rac)-3-Hydroxyphenylglycine (3HPG) is a racemic mixture of (S)-3-hydroxyphenylglycine and (R)-3-hydroxyphenylglycine. (S)-3-Hydroxyphenylglycine is a potent and selective mGluR1 agonist .
Cat. No.: HY-40028
CAS No.: 216854-23-8
Cat. No.: HY-W698462
CAS No.: 35683-15-9
Synonyms: (3S)-3-Hydroxytetradecanoic acid
Target:
Research Areas:
(S)-3-Hydroxymyristic acid ((3S)-3-Hydroxytetradecanoic acid) is the enantiomer of (R)-3-hydroxytetradecanoic acid (a lipid A component) (HY-W288375), and enhances the inherent immune adjuvant activity of lipid A .
Cat. No.: HY-173635
Target:
Research Areas:
Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639) .
Cat. No.: HY-128603
CAS No.: 1383119-39-8
Target:
Research Areas:
2-Hydroxyisobutyryl-CoA is a hydroxy fatty acyl-CoA. 2-Hydroxyisobutyryl-CoA mutase forms the isomer (S)-3-hydroxybutyryl-CoA .
Cat. No.: HY-N2379
CAS No.: 131968-74-6
Research Areas:
Rel-(2R,3S)-3-Phenylisoserine methyl ester is a derivative of serine. Rel-(2R,3S)-3-Phenylisoserine methyl ester can be used as a side chain of Paclitaxel (HY-B0015) .
Cat. No.: HY-N2378
CAS No.: 132201-32-2
Synonyms: Benzenepropanoic acid, β-amino-α-hydroxy-, hydrochloride, (αR,βS)-
Target:
Research Areas:
Cat. No.: HY-I0055
CAS No.: 944716-73-8
Synonyms: Telaprevir Intermediate 4
Target:
Research Areas:
(2S,3S)-3-Amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride (Telaprevir Intermediate 4) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-CE00380
CAS No.: 79171-48-5
Synonyms: (S)-3-Hydroxyoctanoyl-Coenzyme A
Target:
Research Areas:
(S)-3-Hydroxyoctanoyl-CoA ((S)-3-Hydroxyoctanoyl-Coenzyme A) is a hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (S)-3-hydroxyoctanoic acid.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
