(S)-3-Hydroxybutanoic acid
Based on 2 publication(s) in Google Scholar
(S)-3-Hydroxybutanoic acid is a metabolite and a disease marker of depression. 3-Hydroxybutyric acid is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 6168-83-8
- Formula: C4H8O3
- Molecular Weight:104.11
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) (S)-3-Hydroxybutanoic acid
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
(S)-3-Hydroxybutanoic acid affects the basal glucose uptake, and can be used as the alternative source of energy to glucose during fasting[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6168-83-8
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Appearance Solid
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Molecular Weight 104.11
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Formula C4H8O3
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Color Off-white to light yellow
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SMILES
C[C@H](O)CC(O)=O
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Synonyms
(S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Am J Physiol Cell Physiol
Acetoacetate and D- and L-β-hydroxybutyrate have distinct effects on basal and insulin-stimulated glucose uptake in L6 skeletal muscle cells. [Abstract]2024 Jun 1;326(6):C1710-C1720. PMID: 38708524 -
Mol Med Rep
Effects of β‑hydroxybutyric acid and ghrelin on the motility and inflammation of gastric antral smooth muscle cells involving the regulation of growth hormone secretagogue receptor. [Abstract]2019 Dec;20(6):5050-5058. PMID: 31638214
Solvent & Solubility
H2O : 100 mg/mL (960.57 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 9.6057 mL | 48.0284 mL | 96.0569 mL | 240.1422 mL |
| 5 mM | 1.9211 mL | 9.6057 mL | 19.2114 mL | 48.0284 mL | |
| 10 mM | 0.9606 mL | 4.8028 mL | 9.6057 mL | 24.0142 mL | |
| 15 mM | 0.6404 mL | 3.2019 mL | 6.4038 mL | 16.0095 mL | |
| 20 mM | 0.4803 mL | 2.4014 mL | 4.8028 mL | 12.0071 mL | |
| 25 mM | 0.3842 mL | 1.9211 mL | 3.8423 mL | 9.6057 mL | |
| 30 mM | 0.3202 mL | 1.6009 mL | 3.2019 mL | 8.0047 mL | |
| 40 mM | 0.2401 mL | 1.2007 mL | 2.4014 mL | 6.0036 mL | |
| 50 mM | 0.1921 mL | 0.9606 mL | 1.9211 mL | 4.8028 mL | |
| 60 mM | 0.1601 mL | 0.8005 mL | 1.6009 mL | 4.0024 mL | |
| 80 mM | 0.1201 mL | 0.6004 mL | 1.2007 mL | 3.0018 mL | |
| 100 mM | 0.0961 mL | 0.4803 mL | 0.9606 mL | 2.4014 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(S)-3-Hydroxybutanoic acid Related Classifications
HY-W050031 Related Classifications
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