15 Results for "

(R,S,S,S)-Ro-18-0647

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "(R,S,S,S)-Ro-18-0647" in MCE Product Catalog:

37
37 Publications Verification
Cat. No.: HY-B0218
CAS No.: 96829-58-2
Synonyms: Tetrahydrolipstatin; Ro-18-0647
Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity . Anti-atherosclerotic effect .
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12
12 Cited Publications
Cat. No.: HY-B0647
CAS No.: 6066-49-5
Synonyms: 3-n-Butylphthalide; 3-Butylphthalide
Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models.
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4
4 Cited Publications
Cat. No.: HY-N0647
CAS No.: 33889-69-9
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
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1
1 Cited Publications
Cat. No.: HY-101317
CAS No.: 1217628-73-3
Purity:  99.20%
Synonyms: SB-205607 dihydrobromide
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

TAN-67 (SB-205607) dihydrobromide is a potent and selective nonpeptidic δ-opioid receptor agonist with a Ki value of 0.647 nM. TAN-67 dihydrobromide has neuroprotective effect. TAN-67 dihydrobromide can be used in research of ischemic stroke .
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Cat. No.: HY-B0647A
CAS No.: 3413-15-8
Synonyms: (-)-3-n-Butylphthalide; (3S)-Butylphthalide
(3S)-Butylphthalide is a phthalide and can be isolated from A. graveolens. (3S)-Butylphthalide has antiplatelet and neuroprotective activities .
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Cat. No.: HY-B0647S1
CAS No.: 2399464-57-2
Synonyms: 3-n-Butylphthalide-d3; 3-Butylphthalide-d3
Butylphthalide-d3 is the deuterium labeled Butylphthalide. Butylphthalide(3-n-Butylphthalide), an anti-cerebral-ischemia agent, is first isolated from the seeds of celery and showes efficacy in animal models of stroke.
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Cat. No.: HY-B0647R
CAS No.: 6066-49-5
Synonyms: 3-n-Butylphthalide (Standard); 3-Butylphthalide (Standard)
Butylphthalide (Standard) is the analytical standard of Butylphthalide. This product is intended for research and analytical applications. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models.
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Cat. No.: HY-N0647R
CAS No.: 33889-69-9
Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .
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Cat. No.: HY-B0218R
CAS No.: 96829-58-2
Synonyms: Tetrahydrolipstatin (Standard); Ro-18-0647 (Standard)
Orlistat (Standard) is the analytical standard of Orlistat. This product is intended for research and analytical applications. Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity . Anti-atherosclerotic effect .
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Cat. No.: HY-B0218S
CAS No.: 1356930-46-5
Synonyms: Tetrahydrolipstatin-d3; Ro-18-0647-d3
Orlistat-d3 is a deuterated labeled Orlistat . Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN), is used orally for long-term research of obesity .?Anti-atherosclerotic?effect .
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Cat. No.: HY-109502S
10-OH-NBP-d4 is deuterium labeled 10-OH-NBP. 10-OH-NBP is a Butylphthalide (3-n-Butylphthalide; NBP; HY-B0647) hydroxylated metabolite and can penetrates the blood-brain barrier (BBB). Butylphthalide exerts neuroprotective effects and has potential for cerebral ischemia research .
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Cat. No.: HY-173344
Target:  

p38 MAPK

Research Areas:  

Neurological Disease

DB-10 is a pro-agent of 3-nbutylphthalide (NBP) (HY-B0647). DB-10 has significantly high uptake ability via pyrilamine cationic transporters in the temperature and energy dependent manner in cells. DB-10 improves the survival rate of cells. DB-10 could rapidly convert into active original agent and increase the accumulation in the brain in vivo. DB-10 can be used for ischemic stroke study .
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Cat. No.: HY-172298
CAS No.: 104872-28-8
Synonyms: (R,S,S,S)-Tetrahydrolipstatin; (R,S,S,S)-Ro-18-0647
Research Areas:  

Infection

(R,S,S,S)-Orlistat is a stereogenic derivative of orlistat (tetrahydrolipstatin; THL) (HY-B0218). (R,S,S,S)-Orlistat inhibits three Mycobacterium tuberculosis lipid esterases, Ag85C (KI: 16.43 μM), Rv3802 (EC50: 16.2 nM), and Pks13-TE .
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Cat. No.: HY-161980
Target:  

Topoisomerase

Research Areas:  

Infection

Topoisomerases/ribosomes-IN-1 (compound 30f) is an inhibitor of ribosomes and topoisomerases, and has inhibitory effects on constitutively macrolide-resistant bacteria. Topoisomerases/ribosomes-IN-1 can inhibit bacterial protein synthesis (IC50: 0.647 μM) and DNA replication (IC50: 0.218 μM) .
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Cat. No.: HY-P992004
Synonyms: RA15-7, HuRA15-7Acc

Target:  

Folate Receptor (FR)

Research Areas:  

Cancer

KHK2805 (RA15-7) is a humanized antibody against folate receptor α (FOLR1), with a Kd of 0.647 nM for human FOLR1. KHK2805 binds to a unique epitope of FOLR1 and mediates antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against FOLR1-expressing cells. KHK2805 exhibits cytotoxicity against both ovarian cancer cells and Platinum (HY-W096169D)-resistant ovarian cancer cells. KHK2805 can be used for the research of tumors such as ovarian cancer .
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