Silychristin (Standard)
Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM.
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- No. CAS: 33889-69-9
- Fòrmula: C₂₅H₂₂O₁₀
- Peso molecular:482.44
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-N0647
SilychristinMCT8 Inhibitor -
HY-107641
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SaponarinFlavonoid -
HY-107641R
α-Cyano-4-hydroxycinnamic acid (Standard)Reference Standard -
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MCT1-IN-2MCT1 Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 33889-69-9
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Peso molecular 482.44
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Fòrmula C₂₅H₂₂O₁₀
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SMILES
O=C1[C@H](O)[C@@H](C2=CC(O)=C(O[C@@H](C3=CC=C(O)C(OC)=C3)[C@@H]4CO)C4=C2)OC5=CC(O)=CC(O)=C15
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Structure Classification
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Biedermann D, et al. Silychristin: Skeletal Alterations and Biological Activities. J Nat Prod. 2016 Dec 23;79(12):3086-3092. [Content Brief]
[2]. Johannes J, et al. Silychristin, a Flavonolignan Derived From the Milk Thistle, Is a Potent Inhibitor of the Thyroid Hormone Transporter MCT8. Endocrinology. 2016 Apr;157(4):1694-701. [Content Brief]
[3]. Rajnochová Svobodová A, et al. A pilot study of the UVA-photoprotective potential of dehydrosilybin, isosilybin, silychristin, and silydianin on human dermal fibroblasts. Arch Dermatol Res. 2019 Aug;311(6):477-490. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Silychristin (Standard) Related Classifications
HY-N0647R Related Classifications
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