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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
[Ca2+]i
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "[Ca2+]i" in MCE Product Catalog:
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4
4 Cited Publications
Cat. No.: HY-P1410B
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
4
4 Cited Publications
Cat. No.: HY-P1410C
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
2
2 Cited Publications
Cat. No.: HY-P1075
CAS No.: 261969-05-5
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1
1 Cited Publications
Cat. No.: HY-P1366
CAS No.: 293735-04-3
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18:0 LYSO-PE is a lysophospholipid that can induce [Ca 2+]i increase.
Synonyms: DA-6034 free acid
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Recoflavone (DA-6034 (free acid)), a synthetic derivative of the flavonoid Eupatilin (HY-N0783), is orally active. Recoflavone can inhibit the NF-κB pathway and induce [Ca( 2+)]i increase in epithelial cells. Recoflavone exhibits activities such as anti-inflammation, anti-tumor effects, protection of gastric and intestinal mucosa, and promotion of secretion in the ocular surface and salivary glands. Recoflavone can be used for the research of diseases such as dry eye, gastric injury, and intestinal injury [2] .
Cat. No.: HY-P5189A
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Cat. No.: HY-N9404
CAS No.: 99759-48-5
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o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca 2+]i in an agonistic manner .
Synonyms: (E/Z)-Moschamine
Category:
Cardiovascular Disease Alkaloids Carthamus tinctorius L. Phenols Polyphenols Plants Compositae Disease Research Fields Indole Alkaloids
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TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca 2+ concentrations ([Ca 2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals .
Cat. No.: HY-P11082
CAS No.: 126675-52-3
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Cat. No.: HY-103545
CAS No.: 725474-97-5
Synonyms: Gastric inhibitory peptide (1-39) (porcine)
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Cat. No.: HY-113920
CAS No.: 105336-14-9
Synonyms: EU4093
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Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca 2+ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca 2+]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection .
Cat. No.: HY-151547
CAS No.: 2840581-32-8
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MRS4719 is a potent P2X4 receptor antagonist with an IC50 value of 0.503 μM for human P2X4 receptor. MRS4719 can reduce infarct volume and reduce brain atrophy, showing neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4719 also reduces ATP-induced [Ca 2+]i influx in primary human monocyte-derived macrophages. MRS4719 can be used to research ischemic stroke .
Cat. No.: HY-W711474
CAS No.: 1450828-98-4
Cat. No.: HY-132190
CAS No.: 137566-83-7
Synonyms: 1-O-Hexa-decyl-2-acetyl-sn-glycero-3-phospho(N,N,N-trimethyl)-hexanolamine
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Hexanolamino PAF C-16 (1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine) is a Platelet-activating Factor Receptor (PAFR) Modulator with partial agonist activity. Hexanolamino PAF C-16 induces platelet aggregation and macrophage production but fails to increase [Ca2+]i in platelets, suggesting that PAF receptors may interact with PAF receptors through Ca 2+-dependent and -independent pathways. Related to platelet aggregation [2].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
