126675-52-3
Chemical Structure
APGW-amide
- CAS No.: 126675-52-3
- Formula:C21H28N6O4
- Molecular Weight:428.48
InChIKey: UIBASYXNWHWBOR-ZLIFDBKOSA-N
SMILES: O=C(N1[C@@H](CCC1)C(NCC(N[C@@H](CC2=CNC3=CC=CC=C23)C(N)=O)=O)=O)[C@H](C)N
Biological Activity: APGW-amide is a neuropeptide. APGW-amide controls the growth of imposex structures and promotes growth in Haliotis asinina. APGW-amide inhibits Achatina neurons and modulates neuronal currents induced by neuroactive compounds. APGW-amide induces a rapid increase in [Ca2+]i in Fura-2/AM-loaded PC12 cells. APGW-amide is useful for research on the nervous system[1][2][3][4].
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APGW-amide | APGW-amide is a neuropeptide. APGW-amide controls the growth of imposex structures and promotes growth in Haliotis asinina. APGW-amide inhibits Achatina neurons and modulates neuronal currents induced by neuroactive compounds. APGW-amide induces a rapid increase in [Ca2+]i in Fura-2/AM-loaded PC12 cells. APGW-amide is useful for research on the nervous system. | |||||||||||||||||||||
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- [1]. Han XY, et al. Modulation by APGW-amide, an Achatina endogenous inhibitory tetrapeptide, of currents induced by neuroactive compounds on Achatina neurons: amines and amino acids. Gen Pharmacol. 1997 Oct;29(4):523-30. [Content Brief]
- [2]. Han XY, et al. Effect of APGW-amide on [Ca2+]i in rat pheochromocytoma PC12 cells. Jpn J Pharmacol. 2000 Nov;84(3):355-9. [Content Brief]
- [3]. Piyachat Chansela, et al. The Tetrapeptide Apgw-Amide Induces Somatic Growth in Haliotis asinina Linnaeus.
- [4]. Oberdörster E, et al.The neuropeptide APGWamide induces imposex in the mud snail, Ilyanassa obsoleta. Peptides. 2000 Sep;21(9):1323-30. [Content Brief]
Keywords
