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o-3M3FBS 

Cat. No.: HY-108608 Purity: 99.91%
Handling Instructions

o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca2+]i in an agonistic manner.

For research use only. We do not sell to patients.

o-3M3FBS Chemical Structure

o-3M3FBS Chemical Structure

CAS No. : 313981-55-4

Size Price Stock Quantity
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 100 In-stock
Estimated Time of Arrival: December 31
25 mg USD 220 In-stock
Estimated Time of Arrival: December 31
50 mg USD 350 In-stock
Estimated Time of Arrival: December 31
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200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca2+]i in an agonistic manner[1].

In Vivo

o-3M3FBS (10 μM) decreases AUC from 1058±189 g/min in control (in the presence of TTX) to 840±134 g/min. Higher concentration of o-3M3FBS (25 μM) further decreases AUC to 457±59 g/min[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

343.36

Formula

C16H16F3NO2S

CAS No.
SMILES

O=S(C1=C(C)C=C(C)C=C1C)(NC2=CC=CC=C2C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (291.24 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9124 mL 14.5620 mL 29.1240 mL
5 mM 0.5825 mL 2.9124 mL 5.8248 mL
10 mM 0.2912 mL 1.4562 mL 2.9124 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (7.28 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are available by MCE.
References
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Product Name:
o-3M3FBS
Cat. No.:
HY-108608
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