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Art. -Nr.: HY-113920

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Azumolene sodium

(Synonyms: EU4093)

3 Cited Publications

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Based on 3 publication(s) in Google Scholar

Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca²⁺ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca²⁺]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection.

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CAS. Nr.: 105336-14-9
Formel: C₁₃H₉BrN₄NaO₃
Molecular Weight:372.13

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Azumolene sodium Chemical Structure

CAS. Nr.: 105336-14-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS. Nr. 105336-14-9
Molecular Weight 372.13
Formel C₁₃H₉BrN₄NaO₃
SMILES

O=C1NC(CN1/N=C/C2=NC=C(C3=CC=C(Br)C=C3)O2)=O.[Na]
Synonyms

EU4093
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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Journal Impact Factor

Nat Commun

Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development. [Abstract]

2025 Nov 18;16(1):10110. PMID: 41253812
Small

Intranasal Zinc Oxide Nanoparticles Induce Neuronal PANoptosis via Microglial Pathway. [Abstract]

2025 Mar;21(12):e2408139. PMID: 40012250
Cell Death Dis

Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats. [Abstract]

2023 May 13;14(5):325. PMID: 37179386

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Allen P D, Lopez J R, Sanchez V, et al. EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine[J]. Anesthesiology, 1992, 76(1): 132-138.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Azumolene sodium

3 Cited Publications

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Publications (3)
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Azumolene sodium

Publications Citing Use of MedChemExpress (MCE) Azumolene sodium

Alle Calcium Channel Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (3)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Azumolene sodium Related Classifications

HY-113920 Related Classifications