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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
α5-containing subtypes
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "α5-containing subtypes" in MCE Product Catalog:
Cat. No.: HY-189453
Target:
Research Areas:
ETK-II-83 is an orally effective and blood-brain barrier-penetrant ligand for the benzodiazepine site of the GABAA receptor. ETK-II-83 displaces 3H-flunitrazepam from rat brain GABAA receptors and selectively binds to the α5-containing subtype. ETK-II-83 can be used for anxiety research .
Cat. No.: HY-189454
Target:
Research Areas:
ETK-III-9 is an orally active and blood-brain barrier-penetrant GABAA receptor ligand. ETK-III-9 displaces 3H-flunitrazepam at the benzodiazepine site of GABAA receptors, with stronger interactions at α3β3γ2 and α5β3γ2 subtypes. ETK-III-9 exhibits a target IC50 value of 97.8 nM for rat α3/α5-containing GABAA receptors and 7.6 nM for rat α5β3γ2 subtypes. ETK-III-9 is used in anxiety research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
