14 Results for "

β-catenin-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "β-catenin-IN-4" in MCE Product Catalog:

Cat. No.: HY-147651
CAS No.: 2353536-67-9
Purity:  99.84%
Target:  

β-catenin CDK c-Myc

Research Areas:  

Cancer

β-catenin-IN-4 (Compound 39) is a β-catenin inhibitor with a Ki of 0.64 μM. β-catenin-IN-4 reduces the protein expression levels of cyclin D1 and c-Myc .
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14
14 Cited Publications
Cat. No.: HY-101486
CAS No.: 664969-54-4
Purity:  99.55%
Target:  

β-catenin

Research Areas:  

Cancer

LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC50 of 1.65 μM .
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6
6 Cited Publications
Cat. No.: HY-B1360
CAS No.: 72-80-0
Synonyms: ChloquINan
Research Areas:  

Infection Cancer

Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .
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Cat. No.: HY-151520
CAS No.: 912784-79-3
Purity:  99.68%
Target:  

Wnt

Research Areas:  

Cancer

Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission .
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Cat. No.: HY-122649
CAS No.: 1417162-83-4
Purity:  96.92%
Target:  

β-catenin

Research Areas:  

Cancer

UU-T01 is a β-catenin inhibitor with a KD of 0.531 μM. UU-T01 binds to the K435, R469 and K508 residues of β-catenin, disrupting the β-catenin/TCF4 protein-protein interaction .
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Cat. No.: HY-133179
CAS No.: 2131223-69-1
Target:  

Wnt

Research Areas:  

Metabolic Disease

Wnt/β-catenin-IN-4 (compound YW1159) is a potent Wnt/β-catenin inhibitor .
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Cat. No.: HY-124826
CAS No.: 691005-38-6
Synonyms: NSC 109268
Target:  

β-catenin

Research Areas:  

Cancer

BC21 (NSC 109268) is a β-catenin/Tcf4 inhibitor with an IC50 of 5 μM. BC21 effectively inhibits the binding of β-catenin to Tcf4-derived peptides and suppresses β-catenin/Tcf4-driven reporter gene activity. BC21 can be utilized in cancer research .
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Cat. No.: HY-153681
CAS No.: 901751-85-7
Target:  

β-catenin

Research Areas:  

Cancer

β-Catenin modulator-4 (compound IIa-92), an oxazole and thiazole compound, is a potent and selective β-Catenin modulator .
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Cat. No.: HY-157126
CAS No.: 1616974-29-8
Synonyms: PTER-ITC
Target:  

β-catenin

Research Areas:  

Cancer

Pterostilbene-isothiocyanate (PTER-ITC) exhibits potent anticancereffects in vitro. Pterostilbene-isothiocyanate against human osteosarcoma cells by abrogating the β-catenin/TCF-4 interaction .
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Cat. No.: HY-B1360R
CAS No.: 72-80-0
Synonyms: ChloquINan (Standard)
Chlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .
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Cat. No.: HY-133093
CAS No.: 100843-91-2
Synonyms: PKF118-774
Target:  

Parasite β-catenin

Research Areas:  

Infection Cancer

Murayaquinone (PKF118-774) is a β-catenin/Tcf4 complex inhibitor with an IC50 of 2.4 μM. Murayaquinone is a nematicidal agent found in Streptomyces sp. AN140557 .
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Cat. No.: HY-101486R
CAS No.: 664969-54-4
Research Areas:  

Cancer

LF3 (Standard) is the analytical standard of LF3 (HY-101486). This product is intended for research and analytical applications. LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC50 of 1.65 μM .
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Cat. No.: HY-P11660
Research Areas:  

Cancer

β-catenin-IN-10 is a β-catenin:TCF4 interaction inhibitor with an IC50 of 5.44 μM. β-catenin-IN-10 inhibits the Wnt and AR signaling pathways with IC50 values of 0.105 μM and 1.02 μM, respectively. β-catenin-IN-10 suppresses the proliferation of castration-resistant prostate cancer cells. β-catenin-IN-10 is applicable to research related to prostate cancer .
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Cat. No.: HY-181560
CAS No.: 2759011-75-9
Target:  

Wnt β-catenin

Research Areas:  

Metabolic Disease

SLD1121 is an agonist of the Wnt/β-catenin signaling pathway that enhances Wnt signaling by targeting LRP6 (Kd: 4.52-7.49 nM). SLD1121 interacts with the intracellular domain of LRP6, stabilizes LRP6, promotes its nuclear translocation, and facilitates its binding to β-catenin, TCF4 or LEF1 in the nucleus, thereby inducing the expression of Wnt-regulated genes and stem cell-related genes. SLD1121 induces the transition of hair follicles from telogen to anagen in the mouse hair growth cycle and promotes hair growth in mice. SLD1121 is applicable to hair loss-related research .
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