Wnt/β-catenin-IN-4
Wnt/β-catenin-IN-4 (compound YW1159) is a potent Wnt/β-catenin inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 2131223-69-1
- Formula: C19H14FN5O
- Molecular Weight:347.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
1.2 nM
Compound: 3d
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Inhibition of Wnt3a activated Wnt/beta-catenin signaling (unknown origin) expressed in HEK293 cells harboring TCF/LEF-responsive luciferase preincubated with cells followed by Wnt3a addition and measured after 24 hrs by luciferase reporter gene assay
Inhibition of Wnt3a activated Wnt/beta-catenin signaling (unknown origin) expressed in HEK293 cells harboring TCF/LEF-responsive luciferase preincubated with cells followed by Wnt3a addition and measured after 24 hrs by luciferase reporter gene assay
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[PMID: 30605343] |
Chemical Information
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CAS No. 2131223-69-1
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Molecular Weight 347.35
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Formula C19H14FN5O
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SMILES
O=C(NC1=CC=C2C=CC=CC2=N1)C3=C(N(N=N3)C4=C(C=CC=C4)F)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Wnt/β-catenin-IN-4 Related Classifications
HY-133179 Related Classifications
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