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β-glucosidases

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (7) Dengue Virus (1) Drug Derivative (1) Drug Metabolite (1) Endogenous Metabolite (1) Fluorescent Dye (1) Glycosidase (38) Lipoxygenase (1) Reference Standards (2)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (3) Metabolic Disease (13) Neurological Disease (6)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100944

Conduritol B epoxide Maximum Cited Publications 12 Publications Verification	Glycosidase	Neurological Disease
Conduritol B epoxide is an irreversible covalently bound *acid β-glucosidase* (GCase)** inhibitor.

HY-123633

4-Methylumbelliferyl β-D-Glucopyranoside	Glycosidase	Others
4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for *β-glucosidase, utilizes to assay β-glucosidase* activity . 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively .

HY-P2775

β-Glucosidase, almond 1 Publications Verification	Glycosidase	Others
β-Glucosidase, almond is the rate-limiting enzyme in cellulose degradation. β-Glucosidase is a major group among glycoside hydrolases. β-Glucosidase is involved in the degradation of cellulose in soils and has potential for monitoring soil quality .

HY-N2022

Castanospermine 4 Publications Verification	Glycosidase	Inflammation/Immunology Cancer
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .

HY-14829

Afegostat D-Isofagomine; Isofagomine	Glycosidase	Neurological Disease
Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .

HY-15927

4-Nitrophenyl β-D-glucopyranoside 1 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for *β-glucosidase*. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .

HY-13005

Fagomine 5+ Cited Publications D-Fagomine	Glycosidase	Metabolic Disease
Fagomine is a mild glycosidase inhibitor. The K_i of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.

HY-E70038

Endoglycoceramidase II (EGCase II)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase II (EGCase II) is an endo-β-glucosidase that releases intact glycans from ceramides in glycosphingolipids. Endoglycoceramidase II catalyzes the hydrolysis of β-glycosidic linkages between oligosaccharides and ceramides in various glycosphingolipids .

HY-137827

4-Nitrophenyl β-D-Cellobioside p-Nitrophenyl β-D-Cellobioside	Glycosidase	Others
4-Nitrophenyl β-D-Cellobioside (p-Nitrophenyl β-D-cellobioside) is a cellotriose analog. 4-Nitrophenyl β-D-Cellobioside is hydrolyzed by β-glucosidases such as TxGH116 and ThCel7B. 4-Nitrophenyl β-D-Cellobioside can also be hydrolyzed by exoglucanases and endoglucanases to produce p-nitrophenol (PNP). 4-Nitrophenyl β-D-Cellobioside can be used to detect cellulase activity .

HY-14829E

Afegostat D-Tartrate D-Isofagomine D-Tartrate; Isofagomine D-Tartrate	Glycosidase	Neurological Disease
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .

HY-156838

Cyclophellitol aziridine	Glycosidase	Others
Cyclophellitol aziridine is a cyclophenol analogue and a potent β-glucosidase inhibitor .

HY-W039859

2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98%	Biochemical Assay Reagents	Others
2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98% is a substrate for β-glucosidase, used as a bacterial growth medium.

HY-136868

Resorufin-β-D-glucopyranoside, 98% 3-Phenoxazone 7-(β-D-glucopyranoside),98%	Biochemical Assay Reagents	Others
Resorufin-β-D-glucopyranoside, 98% (3-Phenoxazone 7-(β-D-glucopyranoside), 98%) can be used to detect and quantify β-glucosidase activity in various biological samples.

HY-148672

2-Nitrophenyl a-D-glucopyranoside	Glycosidase	Others
2-Nitrophenyl a-D-glucopyranoside is a substrate of β-glucosidase .

HY-14829F

L-Afegostat 5-epi-Isofagomine	Glycosidase	Metabolic Disease
L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an K_i of 30 μM .

HY-N2022R

Castanospermine (Standard)	Reference Standards Glycosidase	Inflammation/Immunology Cancer
Castanospermine is a natural alkaloid that can be extracted from black beans or the Moreton Bay chestnut tree (Castanospermum australae). Castanospermine is an α/ β-glucosidase inhibitor. Castanospermine has anti-inflammatory, antiviral replication and anti-metastatic effects on prostate cancer. Castanospermine can be used as an immunosuppressant to prevent transplant rejection .

HY-N14904

Panosialin D	Glycosidase	Infection
Panosialin D can inhibit α,β-glucosidase and mannose glycosidase. Panosialin D does not inhibit the influenza virus, but it has weak anti-microbial effect .

HY-W013254

2-Nitrophenyl β-D-glucopyranoside	Glycosidase	Others
2-Nitrophenyl β-D-glucopyranoside is a substrate for β-glucosidase. 2-Nitrophenyl β-D-glucopyranoside can be used to test β-glucosidase activity .

HY-14829B

Afegostat tartrate AT 2101; D-Isofagomine tartrate; Isofagomine tartrate	Glycosidase	Neurological Disease
Afegostat tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .

HY-W288349

8-Quinolinyl β-D-glucopyranoside	Biochemical Assay Reagents	Others
8-Quinolinyl β-D-glucopyranoside is an 8-hydroxyquinoline glucoconjugate that can be cleaved in vitro by β-glucosidase .

HY-14829H

Afegostat TFA	Glycosidase	Neurological Disease
Afegostat TFA is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .

HY-N14907

Panosialin wA	Glycosidase	Infection
Panosialin wA can inhibit α,β-glucosidase and mannose glycosidase. Panosialin wA does not inhibit the influenza virus, but it has weak anti-microbial effect .

HY-W357142

3-Acetylumbelliferyl β-D-Glucopyranoside	Fluorescent Dye	Metabolic Disease Inflammation/Immunology
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .

HY-N2383

Validamine (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol	Glycosidase	Metabolic Disease
Validamine competitively inhibits β-glucosidase in a pH-dependent and dose-dependent manner, with an IC₅₀ value of 2.92mM, and the maximum inhibitory ability is at the optimum pH value of this enzyme .

HY-W721582

β,β-Trehalose	Glycosidase	Others
β,β-Trehalose is a analog of trehalose. β,β-Trehalose can support the growth of shoot tips of Cuscuta. β,β-Trehalose can be cleaved by nonspecific *β-glucosidase* .

HY-E70281

Recombinant endoglycoceramidase II rEGCase II	Biochemical Assay Reagents	Metabolic Disease
Recombinant endoglycoceramidase II (rEGCase II) is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Recombinant endoglycoceramidase II catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides in various glycosphingolipids .

HY-N10519

Cellooctaose	Others	Others
Cellooctaose is an oligosaccharide, consisting of eight glucose residues. Cellooctaose is a low-cost polysaccharides in fermentation to hold on Lactococcus lactis recombinant strain growth. Cellooctaose is the substrate of beta-glucosidase (E.C. 3.2.1.21) .

HY-135670

Glycosidase-IN-1	Glycosidase	Metabolic Disease
Glycosidase-IN-1 (Compound 9) is a glycosidase inhibitor synthesized from D-mannose. Glycosidase-IN-1 be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. Glycosidase-IN-1 has hypoglycemic activity .

HY-121586

Nafazatrom Bay g 6575	Lipoxygenase	Cardiovascular Disease
Nafazatrom (Bay g 6575) is an orally active cardioprotective agent that protects against ischemic damage. Nafazatrom dose-dependently inhibits neutrophil aggregation, superoxide anion generation, arachidonic acid metabolism, and to a lesser extent the release of β-glucosidase, platelet aggregation or arachidonic acid in vitro. Acid metabolism has no significant effect. In a dog ischemia-reperfusion model, Nafazatrom (10 mg/kg; po) reduced infarct size and the occurrence of arrhythmias and rescued ischemic myocardial function without affecting any hemodynamic changes. The basis of Nafazatrom's cardioprotection may be inhibition of neutrophil function and cellular infiltration in vitro .

HY-P2775B

β-Glucosidase, Rhizobium etli	Glycosidase	Metabolic Disease
β-Glucosidase, Rhizobium etli (EC 3.2.1.21), is a glucosidase that acts on the β1→4 glycosidic bond connecting two glucose molecules or glucose-substituted molecules (e.g., disaccharide cellobiose). β-Glucosidase is an exonuclease specific for a variety of β-D-glycosidic substrates. β-Glucosidase catalyzes the hydrolysis of the terminal non-reducing residues of β-D-glucosides, releasing glucose.

HY-P2775C

β-Glucosidase, Clostridium thermocellum	Glycosidase	Metabolic Disease
β-Glucosidase, Clostridium thermocellum (EC 3.2.1.21), is a glucosidase that acts on the β1→4 glycosidic bond connecting two glucose molecules or glucose-substituted molecules (e.g., disaccharide cellobiose). β-Glucosidase is an exonuclease specific for a variety of β-D-glycosidic substrates. β-Glucosidase catalyzes the hydrolysis of the terminal non-reducing residues of β-D-glucosides, releasing glucose.

HY-P2775D

β-Glucosidase, Bacteroides fragilis	Glycosidase	Metabolic Disease
β-Glucosidase, Bacteroides fragilis (EC 3.2.1.21), is a glucosidase that acts on the β1→4 glycosidic bond connecting two glucose molecules or glucose-substituted molecules (e.g., disaccharide cellobiose). β-Glucosidase is an exonuclease specific for a variety of β-D-glycosidic substrates. β-Glucosidase catalyzes the hydrolysis of the terminal non-reducing residues of β-D-glucosides, releasing glucose.

HY-N3169

Nyasicol (+)-Nyasicol	Others	Others
Nyasicol ((+)-Nyasicol) is an enzymatic (β-glucosidase) hydrolysis product of Compound 3 .

HY-P2775A

β-Glucosidase(thermostable)	Glycosidase	Metabolic Disease
β-Glucosidase(thermostable) is a glucosidase enzyme located in on the brush border of the small intestine that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose). β-Glucosidase(thermostable) is an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305H

β-Glucosidase 1A, Saccharophagus degradans	Glycosidase	Others
β-Glucosidase 1A, Saccharophagus degradans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305K

β-Glucosidase 1A, Thermus thermophilus	Glycosidase	Others
β-Glucosidase 1A, Thermus thermophilus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305A

β-Glucosidase 1A, Caldicellulosiruptor saccharolyticus	Glycosidase	Others
β-Glucosidase 1A, Caldicellulosiruptor saccharolyticus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305I

β-Glucosidase 1A, Thermobifida fusca	Glycosidase	Others
β-Glucosidase 1A, Thermobifida fusca (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305B

β-Glucosidase 1A, Clostridium cellulovorans	Glycosidase	Others
β-Glucosidase 1A, Clostridium cellulovorans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305D

β-Glucosidase 1A, Pectobacterium carotovorum	Glycosidase	Others
β-Glucosidase 1A, Bacillus halodurans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305

β-Glucosidase 1A, Bacillus halodurans	Glycosidase	Others
β-Glucosidase 1A, Bacillus halodurans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305J

β-Glucosidase 1A, Thermotoga petrophila	Glycosidase	Others
β-Glucosidase 1A, Thermotoga petrophila (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305E

β-Glucosidase 1A, Pyrococcus furiosus	Glycosidase	Others
β-Glucosidase 1A, Pectobacterium carotovorum (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71305C

β-Glucosidase 1A, Paenibacillus polymyxa	Glycosidase	Others
β-Glucosidase 1A, Paenibacillus polymyxa (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-E71306

β-Glucosidase 3A, Bacteroides ovatus	Glycosidase	Others
β-Glucosidase 3A, Bacteroides ovatus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.

HY-W292085

6-Chloro-1H-indol-3-yl β-D-glucopyranoside	Biochemical Assay Reagents	Others
6-Chloro-1H-indol-3-yl β-D-glucopyranoside can be used to detect chromogenic medium for studying yeast with β-glucosidase activity .

HY-N18350

26-Degluco-torvoside H	Glycosidase Drug Derivative	Others
26-Degluco-torvoside H (Compound 4) is a Furostanol glycoside derivative. 26-Degluco-torvoside H forms via hydrolysis of Torvoside H by *β-glucosidase* from Solanum torvum leaves .

HY-100944R

Conduritol B epoxide (Standard)	Reference Standards Glycosidase	Neurological Disease
Conduritol B epoxide (Standard) is the analytical standard of Conduritol B epoxide (HY-100944). This product is intended for research and analytical applications. Conduritol B epoxide is an irreversible covalently bound acid β-glucosidase (GCase) inhibitor.

HY-N18019

Tetrahydro bellidifolin	Drug Metabolite	Metabolic Disease
Tetrahydro bellidifolin (Compound 1a) is the aglycone obtained from the hydrolysis of Tetrahydroswertianolin (HY-N18018) by β-glucosidase. Tetrahydro bellidifolin exhibits significant hepatoprotective activity and reduce serum ALT levels. Tetrahydro bellidifolin can be used for the research of liver injury .

HY-E71288

β-D-Glucopyranosyl abscisate β-glucosidase	Biochemical Assay Reagents	Others
β-D-Glucopyranosyl abscisate β-glucosidase (EC 3.2.1.175) hydrolzes the biologically inactive β-D-Glucopyranosyl ester of abscisic acid to produce active abscisate. Abscisate is a phytohormone critical for plant growth, development and adaption to various stress conditions. The enzyme does not hydrolyse β-D-Glucopyranosyl zeatin.

Cat. No.	Product Name	Type

HY-15927

4-Nitrophenyl β-D-glucopyranoside

1 Publications Verification

Biochemical Assay Reagents

4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .

HY-W039859

2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98%	Biochemical Assay Reagents
2-Chloro-4-nitrophenyl β-D-glucopyranoside, 98% is a substrate for β-glucosidase, used as a bacterial growth medium.

HY-136868

Resorufin-β-D-glucopyranoside, 98% 3-Phenoxazone 7-(β-D-glucopyranoside),98%	Biochemical Assay Reagents
Resorufin-β-D-glucopyranoside, 98% (3-Phenoxazone 7-(β-D-glucopyranoside), 98%) can be used to detect and quantify β-glucosidase activity in various biological samples.

HY-W288349

8-Quinolinyl β-D-glucopyranoside	Biochemical Assay Reagents
8-Quinolinyl β-D-glucopyranoside is an 8-hydroxyquinoline glucoconjugate that can be cleaved in vitro by β-glucosidase .

HY-W292085

6-Chloro-1H-indol-3-yl β-D-glucopyranoside	Biochemical Assay Reagents
6-Chloro-1H-indol-3-yl β-D-glucopyranoside can be used to detect chromogenic medium for studying yeast with β-glucosidase activity .

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β-glucosidases

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