Retinyl glucoside
Retinyl glucoside (Retinyl β-D-glucoside) is a lipid β-D-glucoside of retinol, and also serves as a substrate for broad-spectrum β-glucosidase (β-glucosidase). Retinyl glucoside can be hydrolyzed by guinea pig hepatocyte cytosolic and membrane-associated β-glucosidases as well as almond β-glucosidase to release retinol and glucose, but it is not hydrolyzed by human placental glucocerebrosidase. Retinyl glucoside can be used in the research of Gaucher's disease.
For research use only. We do not sell to patients.
- CAS No.: 136778-12-6
- Formula: C26H40O6
- Molecular Weight:448.59
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Retinyl glucoside (60 min) can be hydrolyzed by almond β-glucosidase in 0.1 M sodium acetate (pH 5.5), releasing nearly equimolar amounts of retinol and glucose, with a glucose/retinol molar ratio of 0.99[1].
Retinyl glucoside (60 min) can be hydrolyzed by guinea pig hepatocellular cytosolic β-glucosidase and membrane-associated TX-100 β-glucosidase in 0.2 M Sodium Citrate (HY-B2201) (pH 6.0)[1].
Retinyl glucoside (1 h) is not hydrolyzed by human placental glucocerebrosidase in 0.1 M sodium acetate (pH 5.5) containing TdC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136778-12-6
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Appearance Solid
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Molecular Weight 448.59
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Formula C26H40O6
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Color Yellow to brown
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SMILES
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(C)CCC1
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Synonyms
Retinyl β-D-glucoside
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Retinyl glucoside Related Classifications
HY-A0058 Related Classifications
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- Retinyl glucoside
- 136778-12-6
- Retinyl β-D-glucoside
- Glycosidase
- retinol
- guinea pig liver membrane-associated (TX-100) β-glucosidase
- gaucher disease
- p-nitrophenyl β-D-glucopyranoside
- human placental glucocerebrosidase
- glucocerebroside
- guinea pig liver cytosolic β-glucosidase
- pNPGlc
- almond β-D-glucosidase
- glucocerebrosidase
- Inhibitor
- inhibitor
- inhibit