Retinyl glucoside
Retinyl glucoside (Retinyl β-D-glucoside) is a lipid β-D-glucoside of retinol, and also serves as a substrate for broad-spectrum β-glucosidase (β-glucosidase). Retinyl glucoside can be hydrolyzed by guinea pig hepatocyte cytosolic and membrane-associated β-glucosidases as well as almond β-glucosidase to release retinol and glucose, but it is not hydrolyzed by human placental glucocerebrosidase. Retinyl glucoside can be used in the research of Gaucher's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 136778-12-6
- 分子式: C26H40O6
- 分子量:448.59
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
体外実験
Retinyl glucoside (60 min) can be hydrolyzed by almond β-glucosidase in 0.1 M sodium acetate (pH 5.5), releasing nearly equimolar amounts of retinol and glucose, with a glucose/retinol molar ratio of 0.99[1].
Retinyl glucoside (60 min) can be hydrolyzed by guinea pig hepatocellular cytosolic β-glucosidase and membrane-associated TX-100 β-glucosidase in 0.2 M Sodium Citrate (HY-B2201) (pH 6.0)[1].
Retinyl glucoside (1 h) is not hydrolyzed by human placental glucocerebrosidase in 0.1 M sodium acetate (pH 5.5) containing TdC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 136778-12-6
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性状 Solid
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分子量 448.59
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分子式 C26H40O6
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Color Yellow to brown
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SMILES
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(C)CCC1
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別名
Retinyl β-D-glucoside
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Retinyl glucoside
- 136778-12-6
- Retinyl β-D-glucoside
- Glycosidase
- retinol
- guinea pig liver membrane-associated (TX-100) β-glucosidase
- gaucher disease
- p-nitrophenyl β-D-glucopyranoside
- human placental glucocerebrosidase
- glucocerebroside
- guinea pig liver cytosolic β-glucosidase
- pNPGlc
- almond β-D-glucosidase
- glucocerebrosidase
- Inhibitor
- inhibitor
- inhibit