1 Result for "

σ1R/H3R antagonist

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "σ1R/H3R antagonist" in MCE Product Catalog:

Cat. No.: HY-181722
Research Areas:  

Neurological Disease

σ1R/H3R ligand-1 is a dual σ1R/H3R antagonist with a σ1R Ki of 8.8 nM and an H3R Ki of 31.2 nM. Through the dual action of simultaneously antagonizing σ1R and H3R, σ1R/H3R ligand-1 exhibits potent dose-dependent analgesic activity in mouse models of visceral pain and neuropathic pain. σ1R/H3R ligand-1 can be used for the research of visceral pain and neuropathic pain .
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