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18 Results for "
NVP (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "NVP (Standard)" in MCE Product Catalog:
Cat. No.: HY-10224R
CAS No.: 404950-80-7
Synonyms: LBH589 (Standard); NVP-LBH589 (Standard)
Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities . Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells . Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma .
Cat. No.: HY-10570R
CAS No.: 129618-40-2
Synonyms: BI-RG 587 (Standard); NSC 641530 (Standard); NVP (Standard)
Nevirapine (Standard) is the analytical standard of Nevirapine. This product is intended for research and analytical applications. Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a Ki of 270 μM .
Cat. No.: HY-15174R
CAS No.: 1028385-32-1
Synonyms: BEZ235 Tosylate (Standard); NVP-BEZ 235 Tosylate (Standard)
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Dactolisib (Tosylate) (Standard) is the analytical standard of Dactolisib (Tosylate). This product is intended for research and analytical applications. Dactolisib Tosylate (BEZ235 Tosylate) is a dual PI3K and mTOR kinase inhibitor with IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively. Dactolisib Tosylate (BEZ235 Tosylate) inhibits mTORC1 and mTORC2.
Cat. No.: HY-14291R
CAS No.: 274901-16-5
Synonyms: LAF237 (Standard); NVP-LAF 237 (Standard)
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Vildagliptin (Standard) is the analytical standard of Vildagliptin. This product is intended for research and analytical applications. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
Cat. No.: HY-16582AR
CAS No.: 956697-53-3
Synonyms: Erismodegib (Standard); LDE225 (Standard); NVP-LDE225 (Standard)
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Sonidegib (Standard) is the analytical standard of Sonidegib. This product is intended for research and analytical applications. Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .
Cat. No.: HY-13203R
CAS No.: 761437-28-9
Synonyms: TAE226 (Standard)
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NVP-TAE 226 (Standard) is the analytical standard of NVP-TAE 226. This product is intended for research and analytical applications. NVP-TAE 226 (TAE226) is a potent and ATP-competitive dual FAK and IGF-1R inhibitor with IC50s of 5.5 nM and 140 nM, respectively. NVP-TAE 226 (TAE226) also effectively inhibits Pyk2 and insulin receptor (InsR) with IC50s of 3.5 nM and 44 nM, respectively .
Cat. No.: HY-13311AR
CAS No.: 1310746-10-1
Synonyms: BGJ-398 phosphate (Standard); NVP-BGJ398 phosphate (Standard)
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Infigratinib phosphate (Standard) is the analytical standard of Infigratinib phosphate. This product is intended for research and analytical applications. Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the FGFR family with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
Cat. No.: HY-13311R
CAS No.: 872511-34-7
Synonyms: BGJ-398 (Standard); NVP-BGJ398 (Standard)
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Infigratinib (Standard) is the analytical standard of Infigratinib. This product is intended for research and analytical applications. Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
Cat. No.: HY-70063R
CAS No.: 944396-07-0
Synonyms: BKM120 (Standard); NVP-BKM120 (Standard)
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Buparlisib (Standard) is the analytical standard of Buparlisib. This product is intended for research and analytical applications. Buparlisib (BKM120; NVP-BKM120) is a pan-class I PI3K inhibitor, with IC50s of 52, 166, 116 and 262 nM for p110α, p110β, p110δ and p110γ, respectively.
Cat. No.: HY-13606R
CAS No.: 404951-53-7
Synonyms: NVP-LAQ824 (Standard); LAQ824 (Standard)
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Dacinostat (Standard) is the analytical standard of Dacinostat. This product is intended for research and analytical applications. Dacinostat is a potent HDAC inhibitor, with an IC50 of 32 nM; Dacinostat also inhibits HDAC1 with an IC50 of 9 nM, and used in cancer research.
Cat. No.: HY-15180R
CAS No.: 1312445-63-8
Synonyms: BKM120 Hydrochloride (Standard); NVP-BKM120 Hydrochloride (Standard)
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Buparlisib (Hydrochloride) (Standard) is the analytical standard of Buparlisib (Hydrochloride). This product is intended for research and analytical applications. Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.
Cat. No.: HY-10215R
CAS No.: 747412-49-3
Synonyms: VER-52296 (Standard); AUY922 (Standard); NVP-AUY922 (Standard)
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Luminespib (Standard) is the analytical standard of Luminespib. This product is intended for research and analytical applications. Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively .
Cat. No.: HY-10192R
CAS No.: 761439-42-3
Synonyms: TAE 684 (Standard)
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NVP-TAE 684 (Standard) is the analytical standard of NVP-TAE 684 (HY-10192). This product is intended for research and analytical applications. NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM .
Cat. No.: HY-10252R
CAS No.: 475488-23-4
Synonyms: ADW742 (Standard); GSK 552602A (Standard); ADW (Standard)
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NVP-ADW742 (Standard) is the analytical standard of NVP-ADW742 (HY-10252). This product is intended for research and analytical applications. NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
Cat. No.: HY-16768R
CAS No.: 872365-14-5
Synonyms: QAW039 (Standard); NVP-QAW039 (Standard)
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Fevipiprant (Standard) is the analytical standard of Fevipiprant. This product is intended for research and analytical applications. Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma .
Cat. No.: HY-10942R
CAS No.: 847559-80-2
Synonyms: NVP-BEP800 (Standard)
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VER-82576 (Standard) is the analytical standard of VER-82576 (HY-10942). This product is intended for research and analytical applications. VER-82576 (NVP-BEP800) is a potent, orally available and selective Hsp90 inhibitor, with an IC50 of 58 nM for Hsp90β; VER-82576 also slightly blocks Grp94 and Trap-1, with IC50s of 4.1 and 5.5 μM, respectively.
Cat. No.: HY-10045R
CAS No.: 497839-62-0
Synonyms: NVP-AEE 788 (Standard)
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AEE788 (Standard) is the analytical standard of AEE788 (HY-10045). This product is intended for research and analytical applications. AEE788 is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively.
Cat. No.: HY-10224AR
CAS No.: 960055-56-5
Synonyms: LBH589 lactate (Standard); NVP-LBH589 lactate (Standard)
Panobinostat lactate (Standard) is the analytical standard of Panobinostat lactate (HY-10224A). This product is intended for research and analytical applications. Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
