761439-42-3
761439-42-3
Chemical Structure
NVP-TAE 684
Synonym(s): TAE 684
- CAS No.: 761439-42-3
- Formula:C30H40ClN7O3S
- Molecular Weight:614.20
IUPAC Name: 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine
InChIKey: QQWUGDVOUVUTOY-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCC(N5CCN(CC5)C)CC4)C=C3OC)=NC=C2Cl)(C(C)C)=O
Biological Activity: NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM[1].
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NVP-TAE 684 | 99.70% | NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM. | ||||||||||||||||||||
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NVP-TAE 684 (Standard) | ≥98% | NVP-TAE 684 (Standard) is the analytical standard of NVP-TAE 684 (HY-10192). This product is intended for research and analytical applications. NVP-TAE 684 (TAE 684) is a highly potent and selective ALK inhibitor, which blocks the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM. | ||||||||||||||||||||
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References
Keywords
