1312445-63-8
1312445-63-8
Chemical Structure
Buparlisib Hydrochloride
Synonym(s): BKM120 Hydrochloride; NVP-BKM120 Hydrochloride
- CAS No.: 1312445-63-8
- Formula:C18H22ClF3N6O2
- Molecular Weight:446.85
IUPAC Name: 5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine hydrochloride
InChIKey: DGPLYAXBXJXEID-UHFFFAOYSA-N
SMILES: NC(N=C1)=CC(C(F)(F)F)=C1C2=NC(N3CCOCC3)=NC(N4CCOCC4)=C2.[H]Cl
Biological Activity: Buparlisib Hydrochloride (BKM120 Hydrochloride) is a CNS-penetrant pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Buparlisib Hydrochloride | 99.51% | Buparlisib Hydrochloride (BKM120 Hydrochloride) is a CNS-penetrant pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively. | ||||||||||||||||||||
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Buparlisib Hydrochloride (Standard) | ≥98% | Buparlisib (Hydrochloride) (Standard) is the analytical standard of Buparlisib (Hydrochloride). This product is intended for research and analytical applications. Buparlisib Hydrochloride (BKM120 Hydrochloride) is a pan-class I PI3K inhibitor, with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively. | ||||||||||||||||||||
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