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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
17β-estradiol
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "17β-estradiol" in MCE Product Catalog:
141
141 Publications Verification
Synonyms: β-estradiol; E2; 17β-estradiol; 17β-Oestradiol
141
141 Publications Verification
Cat. No.: HY-B0141C
CAS No.: 35380-71-3
Synonyms: β-estradiol hemihydrate; 17β-estradiol hemihydrate; 17β-Oestradiol hemihydrate
Category:
33
33 Cited Publications
Synonyms: 2-ME2; NSC-659853
22
22 Cited Publications
Synonyms: β-estradiol 3-benzoate; 17β-estradiol 3-benzoate
Category:
Target:
3
3 Cited Publications
Cat. No.: HY-B0141S1
CAS No.: 66789-03-5
Synonyms: β-estradiol-d4; 17β-estradiol-d4; 17β-Oestradiol-d4
2
2 Cited Publications
Synonyms: β-estradiol (Standard); E2 (Standard); 17β-estradiol (Standard); 17β-Oestradiol (Standard)
2
Category:
Metabolic Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields Steroids
Target:
2
2 Cited Publications
Synonyms: 17β-estradiol 3-sulfate sodium
Target:
Research Areas:
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
2
Target:
Research Areas:
TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC50 value of 9 μM for 17β-estradiol (E2)-ERα. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC50=5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth .
1
Target:
1
1 Cited Publications
Target:
Cat. No.: HY-B0141S2
CAS No.: 221093-45-4
Synonyms: β-estradiol-d5; 17β-estradiol-d5; 17β-Oestradiol-d5
Synonyms: 17β-estradiol 3-sulfate-d4 sodium
Cat. No.: HY-B0141S
CAS No.: 79037-37-9
Synonyms: β-estradiol-d3; 17β-estradiol-d3; 17β-Oestradiol-d3
Target:
Research Areas:
10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen, 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain .
Cat. No.: HY-32876
CAS No.: 16133-25-8
Target:
Research Areas:
Pyridine-3-sulfonyl chloride is a sulfonyl chlorination derivatization reagent for steroidal estrogens. Pyridine-3-sulfonyl chloride reacts with estrogens to form pyridine-3-sulfonyl derivatives, which generate abundant analyte-specific fragment ions upon collision-induced dissociation. Pyridine-3-sulfonyl chloride facilitates quantitative LC-ESI-MS/MS analysis of estrogens in serum and water matrices .
Synonyms: 2-ME2-d5; NSC-659853-d5
Cat. No.: HY-132723AS
Purity: 98.19%
Cat. No.: HY-W008581
CAS No.: 1035-77-4
Synonyms: 3-O-Methyl estradiol; 17β-estradiol 3-methyl ether; 3-Methoxyestradiol
Research Areas:
Estradiol 3-methyl ether (EDME) is a highly selective TRPML1 ion channel antagonist and microtubule (microtubule) depolymerizing agent, with IC50 values of 0.22 μM and 3.8 μM against TRPML1 and TRPML2, respectively; it shows no activity against TRPML3. Estradiol 3-methyl ether induces the disruption of cytoplasmic microtubule networks in mammalian cells, with an EC50 of 9 μM. Independent of estrogen receptors, Estradiol 3-methyl ether blocks autophagy (autophagy), TFEB nuclear translocation, and inhibits the migration and invasion of triple-negative breast cancer cells by suppressing TRPML1. Estradiol 3-methyl ether is applicable for relevant research on triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
