16133-25-8
Chemical Structure
Pyridine-3-sulfonyl chloride
- CAS No.: 16133-25-8
- Formula:C5H4ClNO2S
- Molecular Weight:177.61
IUPAC Name: pyridine-3-sulfonyl chloride
InChIKey: CDRNYKLYADJTMN-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CN=C1)(Cl)=O
Biological Activity: Pyridine-3-sulfonyl chloride is a sulfonyl chlorination derivatization reagent for steroidal estrogens. Pyridine-3-sulfonyl chloride reacts with estrogens to form pyridine-3-sulfonyl derivatives, which generate abundant analyte-specific fragment ions upon collision-induced dissociation. Pyridine-3-sulfonyl chloride facilitates quantitative LC-ESI-MS/MS analysis of estrogens in serum and water matrices[1][2].
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Pyridine-3-sulfonyl chloride | 99.98% | Pyridine-3-sulfonyl chloride is a sulfonyl chlorination derivatization reagent for steroidal estrogens. Pyridine-3-sulfonyl chloride reacts with estrogens to form pyridine-3-sulfonyl derivatives, which generate abundant analyte-specific fragment ions upon collision-induced dissociation. Pyridine-3-sulfonyl chloride facilitates quantitative LC-ESI-MS/MS analysis of estrogens in serum and water matrices. | ||||||||||||||||||||
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- [1]. Xu L, et al. Analysis of steroidal estrogens as pyridine-3-sulfonyl derivatives by liquid chromatography electrospray tandem mass spectrometry. Analytical biochemistry. 2008 Apr 01;375(1):105-14. [Content Brief]
- [2]. Glineur A, et al. Trace analysis of estrogenic compounds in surface and groundwater by ultra high performance liquid chromatography-tandem mass spectrometry as pyridine-3-sulfonyl derivatives. Journal of chromatography. A. 2018 Jan 26;1534:43-54.
Keywords
